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An Histological Approach to the Diagnosis of Neutrophilic Dermatoses

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Neutrophilic Dermatoses

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Abstract

A broad analysis of histological lesions delineate the history of the neutrophilic dermatoses. In all steps of the description of these diseases, the cutaneous biopsy has been essential to ascertain their specificity. Moreover, some of them have been distinguished in accordance with their histological presentation.

The cutaneous biopsy is also one of the major criteria to group dermatoses that are clinically completely different with the common denominator of an aseptic infiltration by neutrophils. They comprise Sweet syndrome, pyoderma gangrenosum, subcorneal pustulosis and erythema elevatum diutinum. Many other dermatoses are characterized by a cutaneous infiltration by neutrophilic have been recognized later and linked to this group.

Skin biopsy is always required for the diagnosis and classification of these rare dermatoses. Finally, it is essential to understand the mechanisms which contribute to cutaneous infiltration by neutrophils.

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Authors and Affiliations

  1. Pathology Department, APHP Hôpital Saint Louis, Paris, France

    Marie-Dominique Vignon-Pennamen M.D.

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  1. Marie-Dominique Vignon-Pennamen M.D.
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Correspondence to Marie-Dominique Vignon-Pennamen M.D. .

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Editors and Affiliations

  1. Physician (Hon.) of Paris Hospitals, Paris, France

    Daniel Wallach

  2. Pathology Department, APHP Hôpital Saint Louis, Paris, France

    Marie-Dominique Vignon-Pennamen

  3. Dipartimento di Fisiopatologia Medico-Chirurgica e dei Trapianti, Universita’ degli Studi di Milano, Unita’ Operativa di Dermatologia, IRCCS Fondazione Ca’ Granda, Ospedale Maggiore Policlinico, Milano, Italy

    Angelo Valerio Marzano

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Vignon-Pennamen, MD. (2018). An Histological Approach to the Diagnosis of Neutrophilic Dermatoses. In: Wallach, D., Vignon-Pennamen, MD., Valerio Marzano, A. (eds) Neutrophilic Dermatoses. Springer, Cham. https://doi.org/10.1007/978-3-319-72649-6_15

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  • DOI: https://doi.org/10.1007/978-3-319-72649-6_15

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