Ovarian cancer is the most lethal gynecological cancer without an effective screening method. Recent research findings point out that type 2 ovarian cancer (high-grade serous carcinoma, carcinosarcoma, and undifferentiated carcinoma) could origin from a premalignant lesion developed in the Fallopian tube, known as serous tubal intraepithelial carcinoma (STIC). Since more than 70% of high-grade serous carcinoma has evidence of STIC, it seems rational to consider whether the salpingectomy would reduce the incidence and death rates from ovarian cancer.
Hysterectomy is one of the most performed gynecological surgical procedures all over the world. If we take the physiopathology of ovarian cancer into account, prophylactic salpingectomy during benign surgeries might reduce the risk of ovarian cancer. The ACOG recommendations in 2015 were focused on discussing with the patient the potential benefits of removing the Fallopian tubes. Randomized controlled trials are needed to support this approach to reduce the incidence of ovarian cancer.
Opportunistic salpingectomy Ovarian epithelial cancer Ovarian reserve Serous tubal intraepithelial carcinoma (STIC) Benign hysterectomy Benign pelvic surgery Tubal ligation
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