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A Mathematical Model of Nucleic Acid Thermodynamics

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Generalized Models and Non-classical Approaches in Complex Materials 1

Part of the book series: Advanced Structured Materials ((STRUCTMAT,volume 89))

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Abstract

The DNA denaturation, the double-stranded DNA unwinding process, is a vital process for cells. The percentage of the denaturation is used as an index of organism complexity and it is the base of the DNA hybridisation technique, which provides a great deal of information. It can be detected by observing the increase in the ability of a DNA solution to absorb ultraviolet light at a wavelength of 260 nm. Based on experimental data, we found a mathematical model capable of predicting the behaviour of a general DNA, given the melting temperature T m .

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Correspondence to Sonia Guarguagli .

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Guarguagli, S., Pastrone, F. (2018). A Mathematical Model of Nucleic Acid Thermodynamics. In: Altenbach, H., Pouget, J., Rousseau, M., Collet, B., Michelitsch, T. (eds) Generalized Models and Non-classical Approaches in Complex Materials 1. Advanced Structured Materials, vol 89. Springer, Cham. https://doi.org/10.1007/978-3-319-72440-9_20

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  • DOI: https://doi.org/10.1007/978-3-319-72440-9_20

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-72439-3

  • Online ISBN: 978-3-319-72440-9

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