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Clinical Aspects in Immunocompetent and Immunocompromised Patients

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The Leishmaniases: Old Neglected Tropical Diseases

Abstract

The clinical aspects of leishmaniasis encompass a spectrum of signs and symptoms. These range from the nodular or ulcerative lesion seen in cutaneous leishmaniasis which, for some Leishmania species, can evolve to mucocutaneous leishmaniasis after dissemination and invasion of the mouth and upper respiratory tract. Further dissemination leads to a rare syndrome known as diffuse cutaneous leishmaniasis. The systemic and most invasive form of the disease is visceral leishmaniasis. These diseases are not only dependent on the infecting Leishmania species, but also on the immunological status of the host. This chapter will address aspects of clinical presentation of leishmaniases both in the immunocompetent and immunocompromised individuals.

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Correspondence to Rojelio Mejia .

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Mejia, R. (2018). Clinical Aspects in Immunocompetent and Immunocompromised Patients. In: Bruschi, F., Gradoni, L. (eds) The Leishmaniases: Old Neglected Tropical Diseases. Springer, Cham. https://doi.org/10.1007/978-3-319-72386-0_6

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