Abstract
Recently, Mg and its alloys have attracted much attention because of their excellent biocompatibility and biodegradability. High anisotropy of Mg crystal structure, however, limits the movement of some slip systems; therefore, pure magnesium possesses poor ductility and/or toughness. A number of studies have revealed that alloying with solute elements and modification of grain structure improved these drawbacks. In this study, to clarify the effect of adding solute elements, e.g., calcium and zinc, impact toughness testing and first-principles calculations of generalized stacking fault energy and grain boundary cohesive energy were conducted. For example, alloying magnesium with calcium and zinc and controlling the microstructure produced a Mg alloy with a high compressive fracture strain of 0.40, which was greater than the estimated maximum strain for fastening a surgical clip. This high fracture strain arose from the enhanced grain boundary cohesive energy and reduced anisotropy of slip systems by solute segregation. As a result, the alloy successfully occluded blood vessels.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
F. Witte, V. Kaese, H. Haferkamp, E. Switzer, A. Meyer-Lindenberg, CJ Wirth, H. Windhagen, In vivo corrosion of four magnesium alloys and the associated bone response, Biomaterials 26 (2005) 3557–3563.
F. Witte, The history of biodegradable magnesium implants: A review, Acta Biomaterialia, 6 (2010), 1680–1692.
Z. Li, X. Gu, S. Lou, Y. Zheng; The development of binary Mg–Ca alloys for use as biodegradable materials within bone, Biomaterials, 29 (2008), 1329–1344.
T. Mukai, M. Yamanoi, H. Watanabe, K. Higashi, Ductility enhancement in AZ31 magnesium alloy by controlling its grain structure, Scripta Materialia, 45 (2001), 89–94.
H. Somekawa, M. Yamaguchi, Y. Osawa, A. Singh, M. Itakura, T. Tsuru, T. Mukai, Material design for magnesium alloys with high deformability, Philosophical Magazine, 95 (2015) 869–885.
N. Ikeo, R. Nakamura, K. Naka, T. Hashimoto, T. Yoshida, T. Urade, K. Fukushima, H. Yabuuchi, T. Fukumoto, Y. Ku, T. Mukai, Fabrication of a magnesium alloy with excellent ductility for biodegradable clips, Acta Biomaterialia., 29 (2016) 468–476.
T. Hase, T. Ohtagaki, M. Yamaguchi, N. Ikeo, T. Mukai, Effect of aluminum or zinc solute addition on enhancing impact fracture toughness in Mg-Ca alloys, Acta Materialia. 104 (2016) 283–294.
J. Rice and J. Wang, Mater. Sci. Eng. A 107, 23 (1989).
M. Yamaguchi, M. Shiga, and H. Kaburaki, Science 307, 393 (2005).
J.T. Chou, K. Ikeda, H. Nakashima, Energy and structure of [1–100] symmetric tilt grain boundaries in magnesium, J. Japan Institute Metals, 69 (2005) 303–307.
Acknowledgements
The author is grateful to Prof. Takumi Fukumoto, Dr. Naoko Ikeo and Mr. Takayuki Hase at Kobe University, Dr. Masatake Yamaguchi at Japan Atomic Energy Agency and Dr. Alok Singh at National Institute for Materials Science for their collaborative works. This work was financially supported by JSPS Grant-in-Aid for Scientific Research in No. 25246012, No. 17H01327 and Hyogo COE Program Promotion Project FY2016.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2018 The Minerals, Metals & Materials Society
About this paper
Cite this paper
Mukai, T. (2018). Material Design for Enhancing Toughness of Mg Alloy and Application for Biodegradable Devices. In: Orlov, D., Joshi, V., Solanki, K., Neelameggham, N. (eds) Magnesium Technology 2018. TMS 2018. The Minerals, Metals & Materials Series. Springer, Cham. https://doi.org/10.1007/978-3-319-72332-7_14
Download citation
DOI: https://doi.org/10.1007/978-3-319-72332-7_14
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-72331-0
Online ISBN: 978-3-319-72332-7
eBook Packages: Chemistry and Materials ScienceChemistry and Material Science (R0)