Skip to main content

Acute or Subacute Pure Generalized Autonomic Failure

  • Chapter
  • First Online:
Evaluation and Management of Autonomic Disorders

Abstract

Clinical case. Differential diagnosis: AAG, Paraneoplastic autonomic neuropathy. Diagnosis: negative antibodies panel for immunological and neoplastic disease, positive anti-ganglionic acetylcholine receptor antibodies (α3 nAChR). Main clinical manifestations of AAG: orthostatic hypotension, gastrointestinal, urinary, sudomotor, erectile and pupillary dysfunction. Immunosuppressive therapy and prognosis.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 64.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 84.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Bibliography

  1. Vernino S, Low PA, Fealey RD, Stewart JD, Farrugia G, Lennon VA. Autoantibodies to ganglionic acetylcholine receptors in autoimmune autonomic neuropathies. N Engl J Med. 2000;343:847–55.

    Article  CAS  PubMed  Google Scholar 

  2. Gibbons CH, Vernino SA, Freeman R. Combined immunomodulatory therapy in autoimmune autonomic ganglionopathy. Arch Neurol. 2008;65:213–7.

    Article  PubMed  Google Scholar 

  3. Koike H, Wanatabe H, Sobue G. The spectrum of immune-mediated autonomic neuropathies: insights from the clinicopathological features. J Neurol Neurosurg Psychiatry. 2013;84:98–106.

    Article  PubMed  Google Scholar 

  4. Winston N, Vernino S. Recent advances in autoimmune autonomic ganglionopathy. Curr Opin Neurol. 2010;23:514–8.

    Article  CAS  PubMed  Google Scholar 

  5. Gibbons CH, Vernino SA, Freeman R. Combined immunomodulatory therapy in autoimmune autonomic ganglionopathy. Arch Neurol. 2008;65(2):213–7.

    Article  PubMed  Google Scholar 

  6. Iodice V, Sandroni P. Autonomic neuropathies. Continuum (Minneap Minn). 2014;20((5 Peripheral Nervous System Disorders)):1373–97.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Juan Idiaquez .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2018 Springer International Publishing AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Idiaquez, J., Benarroch, E., Nogues, M. (2018). Acute or Subacute Pure Generalized Autonomic Failure. In: Idiaquez, J., Benarroch, E., Nogues, M. (eds) Evaluation and Management of Autonomic Disorders. Springer, Cham. https://doi.org/10.1007/978-3-319-72251-1_5

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-72251-1_5

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-72250-4

  • Online ISBN: 978-3-319-72251-1

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics