Abstract
Clinical case. Differential diagnosis: AAG, Paraneoplastic autonomic neuropathy. Diagnosis: negative antibodies panel for immunological and neoplastic disease, positive anti-ganglionic acetylcholine receptor antibodies (α3 nAChR). Main clinical manifestations of AAG: orthostatic hypotension, gastrointestinal, urinary, sudomotor, erectile and pupillary dysfunction. Immunosuppressive therapy and prognosis.
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Bibliography
Vernino S, Low PA, Fealey RD, Stewart JD, Farrugia G, Lennon VA. Autoantibodies to ganglionic acetylcholine receptors in autoimmune autonomic neuropathies. N Engl J Med. 2000;343:847–55.
Gibbons CH, Vernino SA, Freeman R. Combined immunomodulatory therapy in autoimmune autonomic ganglionopathy. Arch Neurol. 2008;65:213–7.
Koike H, Wanatabe H, Sobue G. The spectrum of immune-mediated autonomic neuropathies: insights from the clinicopathological features. J Neurol Neurosurg Psychiatry. 2013;84:98–106.
Winston N, Vernino S. Recent advances in autoimmune autonomic ganglionopathy. Curr Opin Neurol. 2010;23:514–8.
Gibbons CH, Vernino SA, Freeman R. Combined immunomodulatory therapy in autoimmune autonomic ganglionopathy. Arch Neurol. 2008;65(2):213–7.
Iodice V, Sandroni P. Autonomic neuropathies. Continuum (Minneap Minn). 2014;20((5 Peripheral Nervous System Disorders)):1373–97.
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Idiaquez, J., Benarroch, E., Nogues, M. (2018). Acute or Subacute Pure Generalized Autonomic Failure. In: Idiaquez, J., Benarroch, E., Nogues, M. (eds) Evaluation and Management of Autonomic Disorders. Springer, Cham. https://doi.org/10.1007/978-3-319-72251-1_5
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DOI: https://doi.org/10.1007/978-3-319-72251-1_5
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