Abstract
Up to this point, this book has focused primarily on optimization of fixed interventions, in which the intervention design calls for every participant to receive the same treatment. This chapter provides an introduction to adaptive interventions, in which the content, dose, or approach can be varied across participants and across time, with the objective of achieving or maintaining a good outcome for all participants. The multiphase optimization strategy (MOST) can be used to optimize adaptive interventions. This chapter briefly reviews alternative approaches for the optimization trial when an adaptive intervention is to be optimized. Familiarity with the material in all previous chapters, particularly 1–4, is assumed.
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Collins, L.M. (2018). Introduction to Adaptive Interventions. In: Optimization of Behavioral, Biobehavioral, and Biomedical Interventions. Statistics for Social and Behavioral Sciences. Springer, Cham. https://doi.org/10.1007/978-3-319-72206-1_8
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DOI: https://doi.org/10.1007/978-3-319-72206-1_8
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