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Toxicity Assessment in the Nanoparticle Era

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Cellular and Molecular Toxicology of Nanoparticles

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 1048))

Abstract

The wide use of engineered nanomaterials in many fields, ranging from biomedical, agriculture, environment, cosmetic, urged the scientific community to understand the processes behind their potential toxicity, in order to develop new strategies for human safety. As a matter of fact, there is a big discrepancy between the increased classes of nanoparticles and the consequent applications versus their toxicity assessment. Nanotoxicology is defined as the science that studies the effects of engineered nanodevices and nanostructures in living organisms. This chapter analyzes the physico-chemical properties of the most used nanoparticles, the way they enter the living organism and their cytoxicity mechanisms at cellular exposure level. Moreover, the current state of nanoparticles risk assessment is reported and analyzed.

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Authors and Affiliations

  1. Dipartimento di Matematica e Fisica “Ennio De Giorgi”, Università del Salento, Lecce, Italy

    Valeria De Matteis & Rosaria Rinaldi

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  1. Valeria De Matteis
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  2. Rosaria Rinaldi
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Correspondence to Valeria De Matteis .

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Editors and Affiliations

  1. Zoology Department, College of Sciences, King Saud University, Riyadh, Saudi Arabia

    Quaiser Saquib

  2. Department of Botany and Microbiology, College of Sciences, King Saud University, Riyadh, Saudi Arabia

    Mohammad Faisal

  3. Zoology Department, College of Sciences, King Saud University, Riyadh, Saudi Arabia

    Abdulaziz A. Al-Khedhairy

  4. Department of Botany and Microbiology, College of Sciences, King Saud University, Riyadh, Saudi Arabia

    Abdulrahman A. Alatar

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De Matteis, V., Rinaldi, R. (2018). Toxicity Assessment in the Nanoparticle Era. In: Saquib, Q., Faisal, M., Al-Khedhairy, A., Alatar, A. (eds) Cellular and Molecular Toxicology of Nanoparticles. Advances in Experimental Medicine and Biology, vol 1048. Springer, Cham. https://doi.org/10.1007/978-3-319-72041-8_1

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