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Surgical Critical Care Therapy pp 193–207Cite as

Advanced Modalities and Rescue Therapies for Severe Respiratory Failure

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Abstract

This chapter focuses on frequently used adjuncts to traditional mechanical ventilation that are now available in the intensive care unit to manage severe respiratory failure and the acute respiratory distress syndrome (ARDS). Modalities discussed will include airway pressure release ventilation, high-frequency mechanical ventilation, prone positioning, neuromuscular blockade, inhaled selective pulmonary vasodilators nitric oxide and epoprostenol, and ECMO. These advanced modalities for severe respiratory failure will be described in some detail, but this is not intended as a definitive exploration of each topic. Where available, current data supporting each intervention is presented, but, importantly, definitive high-quality evidence is lacking for several of these modalities.

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Authors and Affiliations

  1. Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA

    Charles S. Parsons

  2. Division of Acute Care Surgery, Trauma and Surgical Critical Care, Harvard Medical School, Boston, MA, USA

    Charles H. Cook

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  1. Charles S. Parsons
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Correspondence to Charles H. Cook .

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Editors and Affiliations

  1. Brigham and Womens’s Hospital, Harvard Medical School, Boston, Massachusetts, USA

    Ali Salim

  2. Dell Medical School, University of Texas at Austin, Austin, Texas, USA

    Carlos Brown

  3. Division of Trauma Surgery, Rm C5L100, University of Southern California, Los Angeles, California, USA

    Kenji Inaba

  4. Trauma and Emergency Surgery Service, Legacy Emanuel Medical Center, Portland, Oregon, USA

    Matthew J. Martin

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Parsons, C.S., Cook, C.H. (2018). Advanced Modalities and Rescue Therapies for Severe Respiratory Failure. In: Salim, A., Brown, C., Inaba, K., Martin, M. (eds) Surgical Critical Care Therapy . Springer, Cham. https://doi.org/10.1007/978-3-319-71712-8_18

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