Index Endoscopic Malabsorptive Procedures in Obesity Treatment: Techniques and Outcomes
The obesity epidemic is one of the world’s most daunting problems. According to the World Health Organization, there are more than 1.9 billion adults who are overweight, of which 600 million are obese. Mortality increased significantly throughout the overweight range. Additionally, every 5 units of higher BMI above 25 kg/m2 was associated with ~31% higher risk of premature death. Due to the continued need for alternative therapy, transoral/endoscopic approaches to weight loss are gaining traction as they bridge the gap between need and eligibility. This may allow bariatric procedures to be performed in those individuals who are currently precluded due to multiple comorbidities, older age, mild obesity, atypical anatomy (e.g., adhesions secondary to previous abdominal surgery, a history of gastric resection, or bowel resection), or disease states that affect the bowel. Given the surge in endoscopic therapies for obesity, the purpose of this chapter is to review the techniques and outcomes of specific malabsorptive procedures designed to induce weight loss and/or improve metabolic profiles.
KeywordsEndoscopy Bypass sleeve EndoBarrier ValenTx AspireAssist Magnamosis EndoWindow Fractyl/Glyscend
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