Abstract
Hemophilia A (classic hemophilia) and hemophilia B (Christmas disease) are inherited disorders of coagulation that can produce life-threatening bleeding. Patients with hemophilia will require special management strategies in order to safely undergo dental treatment. Patient management is optimized when the dental professional has a basic understanding of how these diseases affect hemostasis, is familiar with medical/systemic treatment strategies available to the hematologist, and knows the principles of dental/local management of patients with bleeding risks. In order to help with these goals, this chapter reviews the pathophysiology, clinical presentation, patient evaluation, and basics of medical management of hemophilia. These reviews are presented with an emphasis given to the dental management of patients with hemophilia A and B.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Zimmerman B, Valentino LA. Hemophilia: in review. Pediatr Rev. 2013;34:289–95.
Smith JA. Hemophilia: what the oral and maxillofacial surgeon needs to know. Oral Maxillofac Surg Clin North Am. 2016;28:481–9.
Srivastava A, Brewer AK, Mauser-Bunschoten EP, Key NS, Kitchen S, Llinas A, Ludlam CA, Mahlangu JN, Mulder K, Poon MC, Street A. Guidelines for the management of hemophilia. Haemophilia. 2013;19:1–47.
Mensah PK, Gooding R. Surgery in patients with inherited bleeding disorders. Anesthesia. 2015;70:112–20.
Kreuz W, Ettingshausen CE. Inhibitors in patients with haemophilia A. Thromb Res. 2014;134:S22–6.
Ljung RCR. Intracranial hemorrhage in hemophilia A and B. Br J Haematol. 2007;140:378–84.
Balkan C, Kavakli K, Karapinar D. Iliopsoas haemorrhage in patients with haemophilia: results from one centre. Haemophilia. 2005;11:463–7.
Ljung R, Andersson NG. The current status of prophylactic replacement therapy in children and adults with hemophilia. Br J Haematol. 2015;169:777–86.
Rodriguez-Merchan EC. Musculoskeletal complications of hemophilia. HSSJ. 2010;6:37–42.
Franchini M, Zaffanello M, Lippi G. The use of desmopressin in mild hemophilia A. Blood Coagul Fibrinolysis. 2010;21:615–9.
Haberichter SL, Shi Q, Montgomery RR. Regulated release of VWF and FVIII and the biologic implications. Pediatr Blood Cancer. 2006;46:547–53.
Little, James W. Dental management of the medically compromised patient, 7th edn. St. Louis, MO; Mosby, 2008.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2018 Springer International Publishing AG, part of Springer Nature
About this chapter
Cite this chapter
Gangwani, P., Richards, R. (2018). Review of Hemophilia A and B and Perioperative Management in Dentistry. In: Szumita, R., Szumita, P. (eds) Hemostasis in Dentistry. Springer, Cham. https://doi.org/10.1007/978-3-319-71240-6_4
Download citation
DOI: https://doi.org/10.1007/978-3-319-71240-6_4
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-71239-0
Online ISBN: 978-3-319-71240-6
eBook Packages: MedicineMedicine (R0)