Skip to main content
SpringerLink
Log in
Book cover

Target Volume Delineation for Pediatric Cancers pp 125–144Cite as

Rhabdomyosarcoma

  • Chapter
  • First Online:

Part of the book series: Practical Guides in Radiation Oncology ((PGRO))

This is a preview of subscription content, log in via an institution.

References

  1. Li J, Thompson TD, Miller JW et al (2008) Cancer incidence among children and adolescents in the United States, 2001-2003. Pediatrics 121:e1470–e1477

    Article  Google Scholar 

  2. Pappo AS (1995) Rhabdomyosarcoma and other soft tissue sarcomas of childhood. Curr Opin Oncol 7:361–366

    Article  CAS  Google Scholar 

  3. Parham DM (2001) Pathologic classification of rhabdomyosarcomas and correlations with molecular studies. Mod Pathol 14:506–514

    Article  CAS  Google Scholar 

  4. Skapek SX, Anderson J, Barr FG et al (2013) PAX-FOXO1 fusion status drives unfavorable outcome for children with rhabdomyosarcoma: a children’s oncology group report. Pediatr Blood Cancer 60:1411–1417

    Article  Google Scholar 

  5. Arndt CA, Stoner JA, Hawkins DS et al (2009) Vincristine, actinomycin, and cyclophosphamide compared with vincristine, actinomycin, and cyclophosphamide alternating with vincristine, topotecan, and cyclophosphamide for intermediate-risk rhabdomyosarcoma: children’s oncology group study D9803. J Clin Oncol 27:5182–5188

    Article  CAS  Google Scholar 

  6. Walterhouse DO, Pappo AS, Meza JL et al (2014) Shorter-duration therapy using vincristine, dactinomycin, and lower-dose cyclophosphamide with or without radiotherapy for patients with newly diagnosed low-risk rhabdomyosarcoma: a report from the Soft Tissue Sarcoma Committee of the Children’s Oncology Group. J Clin Oncol 32:3547–3552

    Article  CAS  Google Scholar 

  7. Oberlin O, Rey A, Lyden E et al (2008) Prognostic factors in metastatic rhabdomyosarcomas: results of a pooled analysis from United States and European cooperative groups. J Clin Oncol 26:2384–2389

    Article  Google Scholar 

  8. Klem ML, Grewal RK, Wexler LH et al (2007) PET for staging in rhabdomyosarcoma: an evaluation of PET as an adjunct to current staging tools. J Pediatr Hematol Oncol 29:9–14

    Article  Google Scholar 

  9. Eaton BR, McDonald MW, Kim S et al (2013) Radiation therapy target volume reduction in pediatric rhabdomyosarcoma: implications for patterns of disease recurrence and overall survival. Cancer 119:1578–1585

    Article  Google Scholar 

  10. Chen C, Shu HK, Goldwein JW et al (2003) Volumetric considerations in radiotherapy for pediatric parameningeal rhabdomyosarcomas. Int J Radiat Oncol Biol Phys 55:1294–1299

    Article  Google Scholar 

  11. Ermoian RP, Breneman JC, Walterhouse DO et al (2016) Is 45 Gy a sufficient radiation therapy dose for unresected orbital embryonal rhabdomyosarcoma ? A report from the Soft Tissue Sarcoma Committee of the children’s oncology group. Int J Radiat Oncol Biol Phys 96(suppl 2):E548

    Article  Google Scholar 

  12. Neville HL, Andrassy RJ, Lobe TE et al (2000) Preoperative staging, prognostic factors, and outcome for extremity rhabdomyosarcoma: a preliminary report from the Intergroup Rhabdomyosarcoma Study IV (1991-1997). J Pediatr Surg 35:317–321

    Article  CAS  Google Scholar 

  13. Wiener ES, Anderson JR, Ojimba JI et al (2001) Controversies in the management of paratesticular rhabdomyosarcoma: is staging retroperitoneal lymph node dissection necessary for adolescents with resected paratesticular rhabdomyosarcoma? Semin Pediatr Surg 10:146–152

    Article  CAS  Google Scholar 

  14. Casey DL, Wexler LH, LaQuaglia MP et al (2014) Patterns of failure for rhabdomyosarcoma of the perineal and perianal region. Int J Radiat Oncol Biol Phys 89:82–87

    Article  Google Scholar 

  15. Blakely ML, Andrassy RJ, Raney RB et al (2003) Prognostic factors and surgical treatment guidelines for children with rhabdomyosarcoma of the perineum or anus: a report of Intergroup Rhabdomyosarcoma Studies I through IV, 1972 through 1997. J Pediatr Surg 38:347–353

    Article  Google Scholar 

  16. Lawrence W Jr, Anderson JR, Gehan EA et al (1997) Pretreatment TNM staging of childhood rhabdomyosarcoma: a report of the Intergroup Rhabdomyosarcoma Study Group. Children’s Cancer Study Group Pediatric Oncology Group. Cancer 80:1165–1170

    Article  Google Scholar 

  17. Walterhouse DO, Meza JL, Breneman JC et al (2011) Local control and outcome in children with localized vaginal rhabdomyosarcoma: a report from the Soft Tissue Sarcoma committee of the Children’s Oncology Group. Pediatr Blood Cancer 57:76–83

    Article  Google Scholar 

  18. Ladra MM, Edgington SK, Mahajan A et al (2014) A dosimetric comparison of proton and intensity modulated radiation therapy in pediatric rhabdomyosarcoma patients enrolled on a prospective phase II proton study. Radiother Oncol 113:77–83

    Article  Google Scholar 

  19. Cotter SE, Herrup DA, Friedmann A et al (2011) Proton radiotherapy for pediatric bladder/prostate rhabdomyosarcoma: clinical outcomes and dosimetry compared to intensity-modulated radiation therapy. Int J Radiat Oncol Biol Phys 81:1367–1373

    Article  Google Scholar 

  20. Yock T, Schneider R, Friedmann A et al (2005) Proton radiotherapy for orbital rhabdomyosarcoma: clinical outcome and a dosimetric comparison with photons. Int J Radiat Oncol Biol Phys 63:1161–1168

    Article  Google Scholar 

  21. Childs SK, Kozak KR, Friedmann AM et al (2012) Proton radiotherapy for parameningeal rhabdomyosarcoma: clinical outcomes and late effects. Int J Radiat Oncol Biol Phys 82:635–642

    Article  Google Scholar 

  22. Ladra MM, Szymonifka JD, Mahajan A et al (2014) Preliminary results of a phase II trial of proton radiotherapy for pediatric rhabdomyosarcoma. J Clin Oncol 32:3762–3770

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins School of Medicine/Sibley Memorial Hospital, Washington, DC, USA

    Matthew Ladra

  2. Dana Farber/Boston Children’s Cancer and Blood Disorders Center, Department of Radiation Oncology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA

    Karen J. Marcus

  3. Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA, USA

    Torunn Yock

Authors
  1. Matthew Ladra
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Karen J. Marcus
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Torunn Yock
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Matthew Ladra .

Editor information

Editors and Affiliations

  1. Department of Radiation Oncology, Johns Hopkins School of Medicine, Baltimore, MD, USA

    Stephanie A. Terezakis

  2. Department of Radiation Oncology, Massachusetts General Hospital, Harvard University - Medical School, Boston, MA, USA

    Shannon M. MacDonald

Rights and permissions

Reprints and permissions

Copyright information

© 2019 Springer International Publishing AG, part of Springer Nature

About this chapter

Cite this chapter

Ladra, M., Marcus, K.J., Yock, T. (2019). Rhabdomyosarcoma. In: Terezakis, S., MacDonald, S. (eds) Target Volume Delineation for Pediatric Cancers. Practical Guides in Radiation Oncology. Springer, Cham. https://doi.org/10.1007/978-3-319-69140-4_8

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-69140-4_8

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-69139-8

  • Online ISBN: 978-3-319-69140-4

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation