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Overview on Japanese Encephalitis in South and Southeast Asia

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Neglected Tropical Diseases - South Asia

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Abstract

Arboviruses (arthropod-borne viruses) are common causes of debilitating fever syndromes in susceptible human population. Out of more than 500 known arboviruses, about 100 are relevant to human infections and mostly belong to the Flaviviridae, Bunyaviridae, and Togaviridae families [1]. For more than a century, countries in South and Southeast Asia have been under the shadow of one such disease—Japanese encephalitis. As the name suggests, this disease was first reported from the islands of Japan in the year 1871 [2]. Following large-scale epidemic in 1924, the causative agent was isolated in 1933 [3]. The virus, initially named as Japanese encephalitis B virus, was later on characterized to belong to the family Flaviviridae (Latin flavus—yellow) named after the yellow fever virus which was the first member of this family. Apart from yellow fever virus and Japanese encephalitis virus (JEV), this family currently includes over 85 species of viruses including dengue virus, West Nile virus, and the Zika virus [4].

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Acknowledgments

AB is a recipient of the Tata Innovation Fellowship ((BT/HRD/35/01/02/2014)) from the Department of Biotechnology, Ministry of Science and Technology, Government of India.

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Dutta, K., Basu, A. (2017). Overview on Japanese Encephalitis in South and Southeast Asia. In: Singh, S. (eds) Neglected Tropical Diseases - South Asia. Neglected Tropical Diseases. Springer, Cham. https://doi.org/10.1007/978-3-319-68493-2_9

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