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Radionanomedicine pp 411–429Cite as

Molecular Imaging Using Radionanomedicine

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Part of the book series: Biological and Medical Physics, Biomedical Engineering ((BIOMEDICAL))

Abstract

Nanoparticles (NPs) have recently attracted great attention as biomedical imaging agents. Many types of NPs have been investigated with combinations of various molecular targeting groups. In addition, multiplex imaging has been studied with NPs, including surface-enhanced Raman scattering (SERS) NPs. Single-photon emission computed tomography (SPECT) or positron emission tomography (PET) by molecularly targeted, radiolabeled NPs provides several benefits over usual imaging probes in the aspect of sensitivity and quantitation. In addition, multimodal imaging probes that are combinations of both radionuclide-based and non-radionuclide-based imaging approaches, such as optical imaging or magnetic resonance imaging (MRI), could be applied to next medical studies. Furthermore, molecularly targeted probes which could be identified by more than three imaging modalities are possible. In conclusion, nanotechnologies promise to extend the limitations of current molecular imaging techniques, and nanomedicine may play an important role in the future.

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Authors and Affiliations

  1. Department of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, 05505, Republic of Korea

    Yong-il Kim

  2. Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, 03080, Republic of Korea

    Dong Soo Lee

  3. Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, 03080, Republic of Korea

    Dong Soo Lee

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  1. Yong-il Kim
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  1. Department of Nuclear Medicine, Seoul National University, Seoul, Korea (Republic of)

    Dong Soo Lee

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Kim, Yi., Lee, D.S. (2018). Molecular Imaging Using Radionanomedicine. In: Lee, D. (eds) Radionanomedicine. Biological and Medical Physics, Biomedical Engineering. Springer, Cham. https://doi.org/10.1007/978-3-319-67720-0_22

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