Abstract
Physical plasma shows promise as a new therapeutic option for wounds as demonstrated by a growing list of publications of completed clinical studies. Clinical studies in wound healing however pose particular challenges compared to other indications. This essay aims to reflect on some of these challenges and to describe approaches that have been successfully used to address them.
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Notes
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ICH E6 (R2) guideline section 6.
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This applies also to frequently recurring wounds in blistering diseases, e.g., epidermolysis bullosa.
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Zahn, T. (2018). Designing Clinical Studies in Wound Healing. In: Metelmann, HR., von Woedtke, T., Weltmann, KD. (eds) Comprehensive Clinical Plasma Medicine. Springer, Cham. https://doi.org/10.1007/978-3-319-67627-2_28
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DOI: https://doi.org/10.1007/978-3-319-67627-2_28
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