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Comprehensive Clinical Plasma Medicine pp 431–440Cite as

Plasma Activated Medium

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Abstract

Plasma activated medium is a novel therapeutic agent that has anti-tumor effects on a wide variety of cancers. The application of plasma chemistry and molecular cell biology is gradually revealing the nature of plasma-induced physiological outputs. General factors, such as hydrogen peroxide and nitrite ions, are produced through interactions between plasma and air or water. Specific factors that are produced through interactions between plasma and solutes are also important for physiological outputs, such as apoptosis and proliferation. The intracellular molecular mechanisms underlying the anti-tumor effects of plasma activated medium are gradually being elucidated, including the key impacts of intracellular reactive oxygen species on survival and proliferating signaling networks. Animal studies have been conducted to investigate the potential clinical applications of plasma activated medium, including in particular, the treatment of cancer. In the future, many types of plasma activated medium will be developed for a broad range of medical applications.

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Authors and Affiliations

  1. Nagoya University, Nagoya, Japan

    Hiromasa Tanaka & Masaru Hori

Authors
  1. Hiromasa Tanaka
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  2. Masaru Hori
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Corresponding author

Correspondence to Hiromasa Tanaka .

Editor information

Editors and Affiliations

  1. University Medicine Greifswald, Department of Oral and Maxillofacial Surgery/Plastic Surgery, Greifswald, Germany

    Hans-Robert Metelmann

  2. Leibniz Institute for Plasma Science and Technology (INP Greifswald) and University Medicine Greifswald Institute for Hygiene and Environmental Medicine, Greifswald, Germany

    Thomas von Woedtke

  3. Leibniz Institute for Plasma Science and Technology (INP Greifswald), Greifswald, Germany

    Klaus-Dieter Weltmann

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Tanaka, H., Hori, M. (2018). Plasma Activated Medium. In: Metelmann, HR., von Woedtke, T., Weltmann, KD. (eds) Comprehensive Clinical Plasma Medicine. Springer, Cham. https://doi.org/10.1007/978-3-319-67627-2_26

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  • DOI: https://doi.org/10.1007/978-3-319-67627-2_26

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-67626-5

  • Online ISBN: 978-3-319-67627-2

  • eBook Packages: MedicineMedicine (R0)

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