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Designing a Nanocargo with Fe3O4@Au: A Tri-pronged Mechanism for MR Imaging, Synaphic Drug-Delivery, and Apoptosis Induction in Cancer Cells

  • Ravichandran Manisekaran
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Abstract

Cancer, considered as a hallmark of diseases, is responsible for second most mortality and morbidity rates. The greatest discovery in the fundamental cancer biology has not been transformed into clinical therapeutics. There is a vast incongruity existing due to lack of translational medicine targeting towards the cancerous cells both temporally and spatially. Moreover, the drugs available possess a plethora of side effects and are incapable of circumventing the biophysical barriers posed by tumor microphysiology. The two nano-vectors, viz., drug-delivery and imaging have come to the rescue in such a debilitating condition of cancer therapeutics.

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© Springer International Publishing AG 2018

Authors and Affiliations

  • Ravichandran Manisekaran
    • 1
  1. 1.Center for Research and Advanced Studies of the National Polytechnic InstituteMexico CityMexico

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