Skip to main content

Multi-factorial Age Estimation from Skeletal and Dental MRI Volumes

  • Conference paper
  • First Online:
Machine Learning in Medical Imaging (MLMI 2017)

Part of the book series: Lecture Notes in Computer Science ((LNIP,volume 10541))

Included in the following conference series:

Abstract

Age estimation from radiologic data is an important topic in forensic medicine to assess chronological age or to discriminate minors from adults, e.g. asylum seekers lacking valid identification documents. In this work we propose automatic multi-factorial age estimation methods based on MRI data to extend the maximal age range from 19 years, as commonly used for age assessment based on hand bones, up to 25 years, when combined with wisdom teeth and clavicles. Mimicking how radiologists perform age estimation, our proposed method based on deep convolutional neural networks achieves a result of \(1.14 \pm 0.96\) years of mean absolute error in predicting chronological age. Further, when fine-tuning the same network for majority age classification, we show an improvement in sensitivity of the multi-factorial system compared to solely relying on the hand.

D. Štern—This work was supported by the Austrian Science Fund (FWF): P 28078-N33.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Notes

  1. 1.

    Y. Jia, GitHub repository, https://github.com/BVLC/caffe/.

References

  1. Breiman, L.: Random forests. Mach. Learn. 45, 5–32 (2001)

    Article  MATH  Google Scholar 

  2. Demirjian, A., Goldstein, H., Tanner, J.M.: A new system of dental age assessment. Hum. Biol. 45(2), 211–227 (1973)

    Google Scholar 

  3. Greulich, W.W., Pyle, S.I.: Radiographic Atlas of Skeletal Development of the Hand and Wrist, 2nd edn. Stanford University Press, Stanford (1959)

    Google Scholar 

  4. LeCun, Y., Bottou, L., Bengio, Y., Haffner, P.: Gradient-based learning applied to document recognition. Proc. IEEE 86(11), 2278–2324 (1998)

    Article  Google Scholar 

  5. Lindner, C., Bromiley, P.A., Ionita, M.C., Cootes, T.F.: Robust and accurate shape model matching using random forest regression-voting. IEEE Trans. Pattern Anal. Mach. Intell. 37(9), 1862–1874 (2015)

    Article  Google Scholar 

  6. Payer, C., Štern, D., Bischof, H., Urschler, M.: Regressing heatmaps for multiple landmark localization using CNNs. In: Ourselin, S., Joskowicz, L., Sabuncu, M.R., Unal, G., Wells, W. (eds.) MICCAI 2016. LNCS, vol. 9901, pp. 230–238. Springer, Cham (2016). doi:10.1007/978-3-319-46723-8_27

    Chapter  Google Scholar 

  7. Schmeling, A., Geserick, G., Reisinger, W., Olze, A.: Age estimation. Forensic Sci. Int. 165(2–3), 178–181 (2007)

    Article  Google Scholar 

  8. Schmeling, A., Schulz, R., Reisinger, W., Muehler, M., Wernecke, K.D., Geserick, G.: Studies on the time frame for ossification of the medial clavicular epiphyseal cartilage in conventional radiography. Int. J. Leg. Med. 118(1), 5–8 (2004)

    Article  Google Scholar 

  9. Spampinato, C., Palazzo, S., Giordano, D., Aldinucci, M., Leonardi, R.: Deep learning for automated skeletal bone age assessment in X-ray images. Med. Image Anal. 36, 41–51 (2017)

    Article  Google Scholar 

  10. Štern, D., Payer, C., Lepetit, V., Urschler, M.: Automated age estimation from hand MRI volumes using deep learning. In: Ourselin, S., Joskowicz, L., Sabuncu, M.R., Unal, G., Wells, W. (eds.) MICCAI 2016. LNCS, vol. 9901, pp. 194–202. Springer, Cham (2016). doi:10.1007/978-3-319-46723-8_23

    Chapter  Google Scholar 

  11. Štern, D., Urschler, M.: From individual hand bone age estimation to fully automated age estimation via learning-based information fusion. In: 2016 IEEE 13th International Symposium on Biomedical Imaging, pp. 150–154 (2016). doi:10.1109/ISBI.2016.7493232

  12. Tanner, J.M., Whitehouse, R.H., Cameron, N., Marshall, W.A., Healy, M.J.R., Goldstein, H.: Assessment of Skeletal Maturity and Predicion of Adult Height (TW2 Method), 2nd edn. Academic Press, London (1983)

    Google Scholar 

  13. Thodberg, H.H., Kreiborg, S., Juul, A., Pedersen, K.D.: The BoneXpert method for automated determination of skeletal maturity. IEEE Trans. Med. Imaging 28(1), 52–66 (2009)

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Martin Urschler .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2017 Springer International Publishing AG

About this paper

Cite this paper

Štern, D., Kainz, P., Payer, C., Urschler, M. (2017). Multi-factorial Age Estimation from Skeletal and Dental MRI Volumes. In: Wang, Q., Shi, Y., Suk, HI., Suzuki, K. (eds) Machine Learning in Medical Imaging. MLMI 2017. Lecture Notes in Computer Science(), vol 10541. Springer, Cham. https://doi.org/10.1007/978-3-319-67389-9_8

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-67389-9_8

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-67388-2

  • Online ISBN: 978-3-319-67389-9

  • eBook Packages: Computer ScienceComputer Science (R0)

Publish with us

Policies and ethics