Abstract
Clinical practice guidelines (CPGs) serve to transfer results from evidence-based medicine into clinical practice. There is growing interest in clinical decision support systems (CDSS) implementing the guideline recommendations; research on such systems typically considers combinations of workflow languages with knowledge representation formalisms. Here, we report on experience with an OWL-based proof-of-concept implementation of parts of the German S3 guideline for schizophrenia. From the information-technological point of view, the salient feature of our implementation is that it represents the CPG entirely as a logic-based ontology, without resorting, e.g., to rule-based action formalisms or hard-wired workflows to capture clinical pathways. Our current goal is to establish that such an implementation is feasible; long-range benefits we expect from the approach are modularity of CPG implementation, ease of maintenance, and logical unity.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsNotes
- 1.
is open source, and available at http://www8.cs.fau.de/research/cgm.
References
Abidi, S., Abidi, S., Hussain, S., Shepherd, M.: Ontology-based modeling of clinical practice guidelines: A clinical decision support system for breast cancer follow-up interventions at primary care settings. In: MEDINFO 2007, pp. 845–849. IOS Press (2007)
Abidi, S., Cox, J., Abidi, S., Shepherd, M.: Using OWL ontologies for clinical guidelines based comorbid decision support. In: Hawaii International International Conference on Systems Science, HICSS 2012, pp. 3030–3038. IEEE Comp. Soc. (2012)
Beierle, C., Eisele, L., Kern-Isberner, G., Meyer, R.G., Nietzke, M.: Using ontological knowledge about active pharmaceutical ingredients for a decision support system in medical cancer therapy. In: Friedrich, G., Helmert, M., Wotawa, F. (eds.) KI 2016. LNCS, vol. 9904, pp. 119–125. Springer, Cham (2016). doi:10.1007/978-3-319-46073-4_9
Bouamrane, M.-M., Rector, A., Hurrell, M.: A hybrid architecture for a preoperative decision support system using a rule engine and a reasoner on a clinical ontology. In: Polleres, A., Swift, T. (eds.) RR 2009. LNCS, vol. 5837, pp. 242–253. Springer, Heidelberg (2009). doi:10.1007/978-3-642-05082-4_17
Deutsche Gesellschaft für Psychiatrie, Psychotherapie und Nervenheilkunde (ed.) Behandlungsleitlinie Schizophrenie. In: Gaebel, W., Falkai, P. (eds.) Steinkopff, Darmstadt (2006)
Doulaverakis, C., Koutkias, V., Antoniou, G., Kompatsiaris, I.: Applying SPARQL-based inference and ontologies for modelling and execution of clinical practice guidelines: a case study on hypertension management. In: Riaño, D., Lenz, R., Reichert, M. (eds.) KR4HC/ProHealth -2016. LNCS, vol. 10096, pp. 90–107. Springer, Cham (2017). doi:10.1007/978-3-319-55014-5_6
Garg, A., Adhikari, N., McDonald, H., Rosas-Arellano, M., Devereaux, P., Beyene, J., Sam, J., Haynes, R.: Effects of computerized clinical decision support systems on practitioner performance and patient outcomes: a systematic review. JAMA 293, 1223–1238 (2005)
Jafarpour, B., Abidi, S.R., Abidi, S.S.R.: Exploiting semantic web technologies to develop OWL-based clinical practice guideline execution engines. IEEE J. Biomed. Health Inform. 20, 388–398 (2016)
Kashyap, V., Morales, A., Hongsermeier, T.: On implementing clinical decision support: achieving scalability and maintainability by combining business rules and ontologies. In: AMIA Annual Symposium, vol. 2006, pp. 414–418. AMIA (2006)
Martin, D., Burstein, M., McDermott, D., McIlraith, S., Paolucci, M., Sycara, K., McGuinness, D., Sirin, E., Srinivasan, N.: Bringing semantics to web services with OWL-S. World Wide Web, WWW 2007 10, 243–277 (2007)
Mehdi, A., Rudolph, S., Grimm, S.: Epistemic querying of OWL knowledge bases. In: Antoniou, G., Grobelnik, M., Simperl, E., Parsia, B., Plexousakis, D., De Leenheer, P., Pan, J. (eds.) ESWC 2011. LNCS, vol. 6643, pp. 397–409. Springer, Heidelberg (2011). doi:10.1007/978-3-642-21034-1_27
Peleg, M.: Computer-interpretable clinical guidelines: a methodological review. J. Biomed. Inform. 46, 44–763 (2013)
Peleg, M., Tu, S., Bury, J., Ciccarese, P., Fox, J., Greenes, R.A., Hall, R., Johnson, P., Jones, N., Kumar, A., Miksch, S., Quaglini, S., Seyfang, A., Shortliffe, E., Stefanelli, M.: Comparing computer-interpretable guideline models: a case-study approach. J. AMIA 10, 52–68 (2003)
Rector, A., Rogers, J., Zanstra, P., van der Haring, E.: OpenGALEN: Open source medical terminology and tools. In: AMIA Annual Symposium, p. 982. AMIA (2003)
Schulz, S., Stenzhorn, H., Boeker, M., Smith, B.: Strengths and limitations of formal ontologies in the biomedical domain. Rev. Electron. Comun. Inf. Inov. Saude 3, 31–45 (2009)
Sesen, M., Banares-Alcántara, R., Fox, J., Kadir, T., Brady, J.: Lung Cancer Assistant: an ontology-driven, online decision support prototype for lung cancer treatment selection. In: OWL: Experiences and Directions Workshop, OWLED 2012 (2012)
Sirin, E., Parsia, B.: SPARQL-DL: SPARQL query for OWL-DL. In: OWL: Experiences and Directions, OWLED 2007. CEUR Workshop Proceedings, vol. 258 (2007)
Tao, C., Wei, W., Solbrig, H., Savova, G., Chute, C.: CNTRO: A semantic web ontology for temporal relation inferencing in clinical narratives. In: Annual Sympposium on AMIA, pp. 787–791 (2010)
Trivedi, M., Kern, J., Grannemann, B., Altshuler, K., Sunderajan, P.: A computerized clinical decision support system as a means of implementing depression guidelines. Psych. Serv. 55, 879–885 (2004)
Ye, Y., Jiang, Z., Diao, X., Yang, D., Du, G.: An ontology-based hierarchical semantic modeling approach to clinical pathway workflows. Comp. Bio. Med. 39, 722–732 (2009)
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2017 Springer International Publishing AG
About this paper
Cite this paper
Gorín, D., Meyn, M., Naumann, A., Polzer, M., Rabenstein, U., Schröder, L. (2017). Ontological Modelling of a Psychiatric Clinical Practice Guideline. In: Kern-Isberner, G., Fürnkranz, J., Thimm, M. (eds) KI 2017: Advances in Artificial Intelligence. KI 2017. Lecture Notes in Computer Science(), vol 10505. Springer, Cham. https://doi.org/10.1007/978-3-319-67190-1_24
Download citation
DOI: https://doi.org/10.1007/978-3-319-67190-1_24
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-67189-5
Online ISBN: 978-3-319-67190-1
eBook Packages: Computer ScienceComputer Science (R0)