Abstract
Cutting-edge omic strategies are bringing new opportunities to many fields of investigation from the biomedical to the biomedicolegal. Comprehension of molecular mechanisms associated with pathologies such as acute or chronic toxicity or sudden cardiac death and the discovery of associated biomarkers represent key elements in the development of novel routes for a better understanding of complex phenomena. Omics and mining of complex generated data have reached a state of maturity. Recent innovations, notably for mass spectrometry with a remarkable gain in sensitivity and selectivity, and the development of next-generation sequencing technologies, have considerably increased the power of these approaches. In spite of ongoing progress in the omic methodologies, their application can already provide informative results leading to more accurate interpretations and evidences. Beyond the remarkable potential in forensic toxicology such as the research of new biomarkers, we predict that these technologies will reinforce translational research between forensic and clinical disciplines.
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Bararpour, N., Sporkert, F., Augsburger, M., Thomas, A. (2017). Omics in Forensic Toxicology a Bridge Towards Forensic Medicine. In: Ferrara, S. (eds) P5 Medicine and Justice. Springer, Cham. https://doi.org/10.1007/978-3-319-67092-8_31
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DOI: https://doi.org/10.1007/978-3-319-67092-8_31
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