Detection of Tumor Markers and Cell Metabolites in Cell Cultures, Using Nanostructured Chemoresistive Sensors
Nowadays, tumor markers detection is one of the most dynamic field of research for medical technologies, as it seems a reliable source of screening technologies able to both detect neoplasms before their degeneration into malignant forms, and monitor possible relapses after the main cancer removal. On the other hand, studying neoplastic cell cultures behaviour, and their vitality in real time, places problems given to the high proliferation rate of the tumor cells. In this work, nanostructured chemoresistive sensors, sensing unit able to detect volatile chemicals in concentrations up to part per billions, have been used to detect neoplastic markers, with the idea to develop a technology able to follow in real time cell cultures and neoplasms growth, for both research and application in the medical field.
KeywordsSensors Nanotechnology Immortalized cells Cells Biomarkers Metabolites Cell cultures
The authors would like to thank CCIAA of Ferrara for the grant “CCIAA/UNIFE” obtained in 2016, which helped in the realization of this work.
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