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Food Allergen-IgE Impedance Measurements Evaluation in Allergic Children

  • Simona Barni
  • Tommaso Addabbo
  • Ada Fort
  • Matteo Becatti
  • Claudia Fiorillo
  • Marco Mugnaini
  • Niccolò Taddei
  • Valerio Vignoli
  • Elio Novembre
  • Francesca Mori
Conference paper
Part of the Lecture Notes in Electrical Engineering book series (LNEE, volume 457)

Abstract

We propose a new strategy for the evaluation of the interaction between IgE proteins and allergens in allergic subjects by impedance measurements. Additionally, reactive oxygen species (ROS) production in leukocyte subpopulations from non-allergic and allergic children was evaluated. On the basis of our results, these new approaches show advantages in terms of diagnostic efficacy with respect to traditional UNICAP and prick skin tests, which are commercially available nowadays. Here we describe in detail the instrument for impedance evaluation and the measurement protocols, defining univocally, in this way, the overall measurement technique.

Keywords

Impedance measurement Allergy diagnosis ROS production 

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Copyright information

© Springer International Publishing AG 2018

Authors and Affiliations

  • Simona Barni
    • 1
  • Tommaso Addabbo
    • 2
  • Ada Fort
    • 2
  • Matteo Becatti
    • 3
  • Claudia Fiorillo
    • 3
  • Marco Mugnaini
    • 2
  • Niccolò Taddei
    • 3
  • Valerio Vignoli
    • 2
  • Elio Novembre
    • 1
  • Francesca Mori
    • 1
  1. 1.Allergy Unit, Department of PediatricAnna Meyer Children’s University HospitalFlorenceItaly
  2. 2.Department of Information Engineering and MathematicsUniversity of SienaSienaItaly
  3. 3.Department of Experimental and Clinical Biomedical Sciences “Mario Serio”University of FlorenceFlorenceItaly

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