Skip to main content

Above Knee Amputation in the Treatment of Failed Septic Total Knee Arthroplasty

  • Chapter
  • First Online:
The Infected Total Knee Arthroplasty

Abstract

This chapter will review current concepts on above knee amputation (AKA) in the treatment of failed septic total knee arthroplasty (TKA). Most patients are satisfied with their AKA, insomuch as they would have taken an amputation earlier. However, their functional level following AKA for infection is low, with only half of patients managing to walk. More than six previous procedures attempting limb salvage and failed gastrocnemius flap are possible poor prognostic factors. A substantial percentage of patients fail to have a prosthetic limb fitted, and those who do seldom obtain functional independence. Knee fusion (KF) in treatment of recurrent infection after TKA has a better functional and ambulatory result compared to patients receiving AKA. KF patients have significantly higher rates of postoperative infection (14.5% versus 8.3%) and transfusion (55.1% versus 46.8%), whereas AKA patients have a higher rate of systemic complications (31.5% versus 25.9%) and in-hospital mortality (3.7% versus 2.1%). AKA patients have lower hospital charges ($79,686 versus $84,747), longer length of stay (11 versus 7 days), and higher 90-day readmission rate (19.4% versus 16.9%). KF is therefore preferable to AKA for patients who have persistent infected TKA after a failed two-stage reimplantation procedure.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

eBook
USD 16.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 99.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 119.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Fedorka CJ, Chen AF, McGarry WM, Parvizi J, Klatt BA. Functional ability after above-the-knee amputation for infected total knee arthroplasty. Clin Orthop Relat Res. 2011;469:1024–32.

    Article  PubMed  Google Scholar 

  2. Khanna V, Tushinski DM, Soever LJ, Vincent AD, Backstein DJ. Above knee amputation following total knee arthroplasty: when enough is enough. J Arthroplast. 2015;30:658–62.

    Article  Google Scholar 

  3. Rodriguez-Merchan EC. Knee fusion or above-the-knee amputation after failed two-stage reimplantation total knee arthroplasty. Arch Bone Jt Surg. 2015;3:241–3.

    PubMed  PubMed Central  Google Scholar 

  4. Carr JB 2nd, Werner BC, Browne JA. Trends and outcomes in the treatment of failed septic total knee arthroplasty: comparing arthrodesis and above-knee amputation. J Arthroplast. 2016;31:1574–7.

    Article  Google Scholar 

  5. Remes L, Isoaho R, Vahlberg T, Viitanen M, Rautava P. Predictors for institutionalization and prosthetic ambulation after major lower extremity amputation during an eight-year follow-up. Aging Clin Exp Res. 2009;21:129–35.

    Article  PubMed  Google Scholar 

  6. D'Ayala M, Huzar T, Briggs W, Fahoum B, Wong S, Wise L, et al. Blood transfusion and its effect on the clinical outcomes of patients undergoing major lower extremity amputation. Ann Vasc Surg. 2010;24:468–73.

    Article  PubMed  Google Scholar 

  7. Coulston JE, Tuff V, Twine CP, Chester JF, Eyers PS, Stewart AH. Surgical factors in the prevention of infection following major lower limb amputation. Eur J Vasc Endovasc Surg. 2012;43:556–60.

    Article  CAS  PubMed  Google Scholar 

  8. Nelson MT, Greenblatt DY, Soma G, Rajimanickam V, Greenberg CC, Kent KC. Preoperative factors predict mortality after major lower-extremity amputation. Surgery. 2012;152:685–94.

    Article  PubMed  Google Scholar 

  9. O'Brien PJ, Cox MW, Shortell CK, Scarborough JE. Risk factors for early failure of surgical amputations: an analysis of 8,878 isolated lower extremity amputation procedures. J Am Coll Surg. 2013;216:836–42.

    Article  PubMed  Google Scholar 

  10. Wise ES, McMaster WG Jr, Williamson K, Wergin JE, Hocking KM, Brophy CM. Preoperative predictors of 30-day mortality and prolonged length of stay after above-knee amputation. Ann Vasc Surg. 2016;31:124–33.

    Article  PubMed  Google Scholar 

  11. Ziegler-Graham K, MacKenzie EJ, Ephraim PL, Travison TG, Brookmeyer R. Estimating the prevalence of limb loss in the United States: 2005 to 2050. Arch Phys Med Rehabil. 2008;89:422–9.

    Article  PubMed  Google Scholar 

  12. Dillingham TR, Pezzin LE, MacKenzie EJ. Incidence, acute care length of stay, and discharge to rehabilitation of traumatic amputee patients: an epidemiologic study. Arch Phys Med Rehabil. 1998;79:279–87.

    Article  CAS  PubMed  Google Scholar 

  13. Dillingham TR, Pezzin LE, MacKenzie EJ. Limb amputation and limb deficiency: epidemiology and recent trends in the United States. South Med J. 2002;95:875–83.

    PubMed  Google Scholar 

  14. MacKenzie EJ, Castillo RC, Jones AS, Bosse MJ, Kellam JF, Pollak AN, et al. Health-care costs associated with amputation or reconstruction of a limb-threatening injury. J Bone Joint Surg Am. 2007;89:1685–92.

    PubMed  Google Scholar 

  15. Alemayehu B, Warner KE. The lifetime distribution of health care costs. Health Serv Res. 2004;39:627–42.

    Article  PubMed  PubMed Central  Google Scholar 

  16. Blough DK, Hubbard S, McFarland LV, Smith DG, Gambel JM, Reiber GE. Prosthetic cost projections for service members with major limb loss from Vietnam and OIF/OEF. J Rehabil Res Dev. 2010;47:387–402.

    Article  PubMed  Google Scholar 

  17. Naschitz JE, Lenger R. Why traumatic leg amputees are at increased risk for cardiovascular diseases. QJM. 2008;101:251–9.

    Article  CAS  PubMed  Google Scholar 

  18. Kurdibaylo SF. Obesity and metabolic disorders in adults with lower limb amputation. J Rehabil Res Dev. 1996;33:387–94.

    CAS  PubMed  Google Scholar 

  19. Gailey R, Allen K, Castles J, Kucharik J, Roeder M. Review of secondary physical conditions associated with lower-limb amputation and long-term prosthesis use. J Rehabil Res Dev. 2008;45:15–29.

    Article  PubMed  Google Scholar 

  20. Coffey L, Gallagher P, Horgan O, Desmond D, MacLachlan M. Psychosocial adjustment to diabetes-related lower limb amputation. Diabet Med. 2009;26:1063–7.

    Article  CAS  PubMed  Google Scholar 

  21. Schofield CJ, Libby G, Brennan GM, MacAlpine RR, Morris AD, Leese GP. Mortality and hospitalization in patients after amputation a comparison between patients with and without diabetes. Diabetes Care. 2006;29:2252–6.

    Article  PubMed  Google Scholar 

  22. Resnick HE, Carter EA, Sosenko JM, Henly SJ, Fabsitz RR, Ness FK, et al. Incidence of lower-extremity amputation in American Indians the strong heart study. Diabetes Care. 2004;27:1885–91.

    Article  PubMed  Google Scholar 

  23. Kalbaugh CA, Taylor SM, Kalbaugh BA, Halliday M, Daniel G, Cass AL, et al. Does obesity predict functional outcome in the dysvascular amputee? Am Surg. 2006;72:707–13.

    PubMed  Google Scholar 

  24. Smith DG, Michael JW, Bowker JH, Surgeons AAOO. Atlas of amputations and limb deficiencies: surgical, prosthetic, and rehabilitation principles. 3rd ed. Rosemont: American Academy of Orthopaedic Surgeons; 2004. isbn:0-89203-313-4.

    Google Scholar 

  25. Lusardi MM, Jorge M, Nielsen CC. Orthotics and prosthetics in rehabilitation. 3rd ed. Amsterdam: Elsevier Health Sciences; 2013. isbn:9781437719369.

    Google Scholar 

  26. Al Muderis M, Khemka A, Lord SJ, Van de Meent H, Frölke JP. Safety of osseointegrated implants for transfemoral amputees: a two-center prospective cohort study. J Bone Joint Surg Am. 2016;98:900–9.

    Article  PubMed  Google Scholar 

  27. Ehde DM, Czerniecki JM, Smith DG, Campbell KM, Edwards WT, Jensen MP, et al. Chronic phantom sensations, phantom pain, residual limb pain, and other regional pain after lower limb amputation. Arch Phys Med Rehabil. 2000;81:1039–44.

    Article  CAS  PubMed  Google Scholar 

  28. Meier RH, Atkins DL. Functional restoration of adults and children with upper extremity amputation. New York: Demos Medical; 2004. isbn:1-888799-73-0.

    Google Scholar 

  29. Sherman RA, Sherman CJ, Gall NG. A survey of current phantom limb pain treatment in the United States. Pain. 1980;8:85–99.

    Article  CAS  PubMed  Google Scholar 

  30. Uustal H, Meier RH. Pain issues and treatment of the person with an amputation. Phys Med Rehabil Clin N Am. 2014;25:45–52.

    Article  PubMed  Google Scholar 

  31. Pantall A, Ewins D. Muscle activity during stance phase of walking: comparison of males with transfemoral amputation with osseointegrated fixations to nondisabled male volunteers. J Rehabil Res Dev. 2013;50:499–514.

    Article  PubMed  Google Scholar 

  32. Hafner BJ, Willingham LL, Buell NC, Allyn KJ, Smith DG. Evaluation of function, performance, and preference as transfemoral amputees transition from mechanical to microprocessor control of the prosthetic knee. Arch Phys Med Rehabil. 2007;88:207–17.

    Article  PubMed  Google Scholar 

  33. Williams RM, Turner AP, Orendurff M, Segal AD, Klute GK, Pecoraro J, et al. Does having a computerized prosthetic knee influence cognitive performance during amputee walking? Arch Phys Med Rehabil. 2006;87:989–94.

    Article  PubMed  Google Scholar 

  34. Wolf EJ, Everding VQ, Linberg AA, Czerniecki JM, Gambel JM. Comparison of the power knee and c-leg during step-up and sit-to-stand tasks. Gait Posture. 2013;38:397–402.

    Article  PubMed  Google Scholar 

  35. Everding VQ, Czerniecki JM, Gambel JM. Assessment of transfemoral amputees using c-leg and power knee for ascending and descending inclines and steps. J Rehabil Res Dev. 2012;49:831–42.

    Article  PubMed  Google Scholar 

  36. Kistenberg RS. Prosthetic choices for people with leg and arm amputations. Phys Med Rehabil Clin N Am. 2014;25:93–115.

    Article  PubMed  Google Scholar 

  37. Czerniecki JM. Research and clinical selection of foot-ankle systems. J Prosthet Orthot. 2005;17:S35–7.

    Article  Google Scholar 

  38. Daher RL. Physical response of SACH feet under laboratory testing. Bull Prosthet Res. 1974;4:50.

    Google Scholar 

  39. Herr HM, Grabowski AM. Bionic ankle--foot prosthesis normalizes walking gait for persons with leg amputation. Proc Biol Sci. 2012;279(1728):457–64.

    Article  PubMed  Google Scholar 

  40. Passero T. Devising the prosthetic prescription and typical examples. Phys Med Rehabil Clin N Am. 2014;25:117–32.

    Article  PubMed  Google Scholar 

  41. Meier RH, Heckman JT. Principles of contemporary amputation rehabilitation in the United States. Phys Med Rehabil Clin N Am. 2014;25:29–33.

    Article  PubMed  Google Scholar 

  42. Belon HP, Vigoda DF. Emotional adaptation to limb loss. Phys Med Rehabil Clin. 2014;25:53–74.

    Article  Google Scholar 

  43. Roberts TL, Pasquina PF, Nelson VS, Flood KM, Bryant PR, Huang ME. Limb deficiency and prosthetic management. 4. Comorbidities associated with limb loss. Arch Phys Med Rehabil. 2006;87:21–7.

    Article  Google Scholar 

  44. Darnall BD, Ephraim P, Wegener ST, Dillingham T, Pezzin L, Rossbach P, et al. Depressive symptoms and mental health service utilization among persons with limb loss: results of a national survey. Arch Phys Med Rehabil. 2005;86:650–8.

    Article  PubMed  Google Scholar 

  45. Wegener ST, Mackenzie EJ, Ephraim P, Ehde D, Williams R. Self-management improves outcomes in persons with limb loss. Arch Phys Med Rehabil. 2009;90:373–80.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to E. Carlos Rodríguez-Merchán .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2018 Springer International Publishing AG

About this chapter

Cite this chapter

Rodríguez-Merchán, E.C., de la Corte-Rodriguez, H., Román-Belmonte, J.M. (2018). Above Knee Amputation in the Treatment of Failed Septic Total Knee Arthroplasty. In: Rodríguez-Merchán, E., Oussedik, S. (eds) The Infected Total Knee Arthroplasty. Springer, Cham. https://doi.org/10.1007/978-3-319-66730-0_21

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-66730-0_21

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-66729-4

  • Online ISBN: 978-3-319-66730-0

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics