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Protein Basics

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A Mathematical Approach to Protein Biophysics

Part of the book series: Biological and Medical Physics, Biomedical Engineering ((BIOMEDICAL))

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Abstract

It is not our intention to provide a complete introduction to the structure of proteins. Instead, we suggest consulting texts (Branden, Tooze, Introduction to protein structure. Garland Pub., New York, 1991, [59], Thomas, Creighton, proteins: structures and molecular properties. W. H. Freeman, New York, 1993, [102], Petsko, Ringe, Protein structure and function. New Science Press, London, 2004, [393]) for further information. Moreover, we suggest acquiring a molecular modeling set so that accurate three-dimensional models can be constructed. In addition, it will be useful to become familiar with a graphical viewer for PDB files (even the venerable “rasmol” would be useful). We present some essential information and emphasize concepts needed later or ones that may be novel.

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Notes

  1. 1.

    There are more than twenty biologically related amino acids that have been identified, but we will limit our study to the twenty primary amino acids commonly found.

  2. 2.

    In this regard tryptophan shares structure similar to the compound psilocybin which is known to fit into the same binding sites as the neurotransmitter serotonin.

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Correspondence to L. Ridgway Scott .

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Scott, L.R., Fernández, A. (2017). Protein Basics. In: A Mathematical Approach to Protein Biophysics. Biological and Medical Physics, Biomedical Engineering. Springer, Cham. https://doi.org/10.1007/978-3-319-66032-5_4

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