A 67-year-old male had a history of a right calf deep venous thrombosis (DVT) following a flight from California to New York. He was treated on that occasion with anticoagulation with unfractionated heparin then Coumadin for 3 months. Recently, he was diagnosed with sigmoid cancer. He is now on postoperative day 3 from exploratory laparotomy, sigmoid colectomy and extensive lysis of adhesions. Although he was haemodynamically stable, he required a transfusion of three units of blood. DVT prophylaxis for the perioperative period included graded knee-high compressive stockings and intermittent pneumatic compression (IPC).
What are the risk factors that predispose to DVT?
What is the clinical presentation of a patient with anti-thrombin III (ATIII) deficiency?
Procainamide has been associated with the development of APA syndrome.
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