Cardiovascular Risk Factors and Peripheral Arterial Disease

  • Stella S. Daskalopoulou
  • Dimitri P. Mikhailidis

Case Report

A 62-year-old man with intermittent claudication was referred for vascular risk factor modification. He had no history of myocardial infarction (MI) or stroke. He was smoking 20 cigarettes/day. His family history was negative for premature vascular events in first degree relatives. He was not taking any medication. He was advised to start aspirin 75 mg/day, but he stopped taking these tablets because of “stomach discomfort”. The patient’s total cholesterol was 228 mg/dL (5.9 mmol/L). His blood pressure required treatment with amlodipine and a thiazide diuretic. The patient eventually stopped smoking after referral to the smoking cessation clinic in our hospital.

Question 1

Which of the following investigations would you order?
  1. A.

    Fasting plasma glucose.

  2. B.

    Urine glucose to make a diagnosis of diabetes mellitus.

  3. C.

    Fasting serum triglycerides.

  4. D.

    Fasting serum high-density lipoprotein cholesterol (HDL-C).

  5. E.

    Thyroid function tests.


Question 2

What drug would you...


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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Stella S. Daskalopoulou
    • 1
  • Dimitri P. Mikhailidis
    • 2
  1. 1.Faculty of Medicine, Divisions of Internal Medicine and Experimental Medicine, Department of MedicineMcGill UniversityMontrealCanada
  2. 2.Department of Clinical BiochemistryRoyal Free Hospital Campus, University College London Medical School, University College LondonLondonUK

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