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Image-Guided Radiofrequency Ablation for Small Renal Masses

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The Management of Small Renal Masses

Abstract

The diagnosis of incidental small renal masses (SRM) has increased during the past two decades secondary to the increased use of various abdominal imaging modalities. In the past decade, there has been a shift from radical nephrectomy to nephron-sparing surgery techniques where partial nephrectomy has become the standard of care. Thermal ablation (TA) modalities such as freezing or heating delivered percutaneously for the treatment of small renal masses (SRM) are now offered in most institutions as a treatment option. Clinical guidelines have indicated that TA is appropriate for select patients that are medically high risk or elderly. In our institution and in select centres, TA is discussed and often offered for all patients with SRM as equivalent treatment without respect to age or co-morbidities. As provider experience improves and long-term outcome studies become available, TA is becoming increasingly accepted as a potential new standard of care for solid SRM. This review will highlight the role of image-guided radiofrequency ablation (RFA) techniques and their application focusing on the different imaging modalities for RFA application which, most commonly, include percutaneous (magnetic resonance imaging (MRI) and computerized tomography (CT)). Our aim is to summarize those studies along with long-term follow-up.

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Abbreviations

CA:

Cryoablation

EMN:

Electromagnetic navigation

MWA:

Microwave ablation

NSS:

Nephron-sparing surgery

PN:

Partial nephrectomy

RCC:

Renal cell carcinoma

RFA:

Radiofrequency ablation

RN:

Radical nephrectomy

SRM:

Small renal masses

TA:

Thermal ablation

References

  1. Glamore M, Leveillee R. CT-guided renal ablation. In: Liao JC, Su L, editors. Advances in image-guided urologic surgery. New York: Springer; 2015. p. 175–84. doi:10.1007/978-1-4939-1450-0.

    Google Scholar 

  2. Ordon M, Findeiss L, Landman J. MR-guided renal ablation. In: Liao JC, Su L, editors. Advances in image-guided urologic surgery. New York: Springer; 2015. p. 185–99. doi:10.1007/978-1-4939-1450-0.

    Google Scholar 

  3. Campbell SC, Novick AC, Belldegrun A, et al. Guideline for management of the clinical T1 renal mass. J Urol. 2009;182(4):1271–9.

    Article  PubMed  Google Scholar 

  4. Sterrett SP, Nakada SY, Wingo MS, Williams SK, Leveillee RJ. Renal thermal ablative therapy. Urol Clin North Am. 2008;35(3):397–414.

    Article  PubMed  Google Scholar 

  5. Castro A Jr, Jenkins LC, Salas N, Lorber G, Leveillee RJ. Ablative therapies for small renal tumours. Nat Rev Urol. 2013;10(5):284–91.

    Article  PubMed  Google Scholar 

  6. Castle SM, Gorbatiy V, Avallone MA, Eldefrawy A, Caulton DE, Leveillee RJ. Cost comparison of nephron-sparing treatments for cT1a renal masses. Urol Oncol. 2013;31(7):1327–32.

    Article  PubMed  Google Scholar 

  7. Gorin MA, Gahan J, Antebi E, Carey RI, Bird VG. Laparoscopic-guided radiofrequency ablation is safe for the treatment of enhancing renal masses among patients prescribed antithrombotic agents. Clin Appl Thromb Hemost. 2012;18(1):35–9.

    Article  PubMed  Google Scholar 

  8. Zagoria RJ, Pettus JA, Rogers M, Werle DM, Childs D, Leyendecker JR. Long-term outcomes after percutaneous radiofrequency ablation for renal cell carcinoma. Urology. 2011;77(6):1393–7.

    Article  PubMed  Google Scholar 

  9. Olweny EO, Park SK, Tan YK, Best SL, Trimmer C, Cadeddu JA. Radiofrequency ablation versus partial nephrectomy in patients with solitary clinical T1a renal cell carcinoma: comparable oncologic outcomes at a minimum of 5 years of follow-up. Eur Urol. 2012;61(6):1156–61.

    Article  PubMed  Google Scholar 

  10. Psutka SP, Feldman AS, McDougall WS, et al. Long-term oncologic outcomes after radiofrequency ablation for T1 renal cell carcinoma. Eur Urol. 2013;63(3):486–92.

    Article  PubMed  Google Scholar 

  11. Salas N, Castle SM, Leveillee RJ. Radiofrequency ablation for treatment of renal tumours: technological principles and outcomes. Expert Rev Med Devices. 2011;8(6):695–707.

    Article  PubMed  Google Scholar 

  12. Wingo MS, Leveillee RJ. Central and deep renal tumours can be effectively ablated: radiofrequency ablation outcomes with fibre optic peripheral temperature monitoring. J Endourol. 2008;22(6):1261–7.

    Article  PubMed  Google Scholar 

  13. Lorber G, Glamore M, Doshi M, Jorda M, Morillo-Burgos G, Leveillee RJ. Long-term oncologic outcomes following radiofrequency ablation with real-time temperature monitoring for T1a renal cell cancer. Urol Oncol. 2014;32(7):1017–23.

    Article  PubMed  Google Scholar 

  14. Ferakis N, Bouropoulos C, Granitsas T, Mylona S, Poulias I. Long-term results after computed-tomography-guided percutaneous radiofrequency ablation for small renal tumours. J Endourol. 2010;24(12):1909–13.

    Article  PubMed  Google Scholar 

  15. Carey RI, Leveillee RJ. First prize: direct real-time temperature monitoring for laparoscopic and CT-guided radiofrequency ablation of renal tumours between 3 and 5 cm. J Endourol. 2007;21(8):807–13.

    Article  PubMed  Google Scholar 

  16. Lay AH, Faddegon S, Olweny EO, et al. Oncologic efficacy of radio frequency ablation for small renal masses: clear cell vs papillary subtype. J Urol. 2015;194(3):653–7.

    Article  PubMed  Google Scholar 

  17. Uppot RN, Silverman SG, Zagoria RJ, Tuncali K, Childs DD, Gervais DA. Imaging-guided percutaneous ablation of renal cell carcinoma: a primer of how we do it. AJR Am J Roentgenol. 2009;192(6):1558–70.

    Article  PubMed  Google Scholar 

  18. Fallone BG, Moran PR, Podgorsak EB. Noninvasive thermometry with a clinical x-ray CT scanner. Med Phys. 1982;9:715–21.

    Article  CAS  PubMed  Google Scholar 

  19. Cheng EY, Naranje SM, Ritenour ER. Radiation dosimetry of intraoperative cone-beam compared with conventional CT for radiofrequency ablation of osteoid osteoma. J Bone Joint Surg Am. 2014;96(9):735–42.

    Article  PubMed  Google Scholar 

  20. Leveillee RJ, Castle SM, Salas N, Doshi M, Gorbatiy V, O’Neill W. Improved targeting of radio-frequency ablation probes and thermal sensors: a preliminary investigation of flat-panel CT guided ablation of renal tumours in the cardiac catheterization lab. J Endourol. 2011;25(7):1119–23.

    Article  PubMed  Google Scholar 

  21. Krucker J, Xu S, Venkatesan A, et al. Clinical utility of real-time fusion guidance for biopsy and ablation. J Vasc Interv Radiol. 2011;22(4):515–24.

    Article  PubMed  PubMed Central  Google Scholar 

  22. Leveillee RJ, Ramanathan R. Optimization of image-guided targeting in renal focal therapy. J Endourol. 2010;24(5):729–44.

    Article  PubMed  Google Scholar 

  23. Venkatesan AM, Kadoury S, Abi-Jaoudeh N, et al. Real-time FDG PET guidance during biopsies and radiofrequency ablation using multimodality fusion with electromagnetic navigation. Radiology. 2011;260(3):848–56.

    Article  PubMed  PubMed Central  Google Scholar 

  24. Hung AJ, Ma Y, Zehnder P, Nakamoto M, Gill IS, Ukimura O. Percutaneous radiofrequency ablation of virtual tumours in canine kidney using global positioning system-like technology. BJU Int. 2012;109(9):1398–403.

    Article  PubMed  Google Scholar 

  25. Venkatesan AM, Wood BJ, Gervais DA. Percutaneous ablation in the kidney. Radiology. 2011;261(2):375–91.

    Article  PubMed  PubMed Central  Google Scholar 

  26. Boss A, Clasen S, Kuczyk M, Schick F, Pereira PL. Image-guided radiofrequency ablation of renal cell carcinoma. Eur Radiol. 2007;17(3):725–33.

    Article  PubMed  Google Scholar 

  27. Hong J, Dohi T, Hasizume M, Konishi K, Hata N. Ultrasound guided motion adaptive instrument for percutaneous needle insertion therapy. In: 6th International conference on biomedical engineering and rehabilitation engineering. China: Guilin; 2002. p. 225–7.

    Google Scholar 

  28. Solomon SB, Patriciu A, Bohlman ME, et al. Robotically driven interventions: a method of using CT fluoroscopy without radiation exposure to the physician. Radiology. 2002;225:277–82.

    Article  PubMed  PubMed Central  Google Scholar 

  29. Jacobi V, Thalihammer A, Kirchner J. Value of a laser guidance system for CT interventions: a phantom study. Eur Radiol. 1999;9:137–40.

    Article  CAS  PubMed  Google Scholar 

  30. Lehman DS, Hruby GW, Phillips CK, McKiernan JM, Benson MC, Landman J. First prize (tie): laparoscopic renal cryoablation: efficacy and complications for larger renal masses. J Endourol. 2008;22(6):1123–7.

    Article  PubMed  Google Scholar 

  31. Farrell MA, Charboneau JW, Callstrom MR, Reading CC, Engen DE, Blute ML. Paranephric water instillation: a technique to prevent bowel injury during percutaneous renal radiofrequency ablation. AJR Am J Roentgenol. 2003;181(5):1315–7.

    Article  CAS  PubMed  Google Scholar 

  32. Haas NB. Surveillance for renal cell cancer recurrence: which patients should undergo imaging, how often, and when? J Clin Oncol. 2015;33(35):4131–3.

    Article  PubMed  Google Scholar 

  33. Ma Y, Bedir S, Cadeddu JA, Gahan JC. Long-term outcomes in healthy adults after radiofrequency ablation of T1a renal tumours. BJU Int. 2014;113(1):51–5.

    Article  PubMed  Google Scholar 

  34. Kim SD, Yoon SG, Sung GT. Radiofrequency ablation of renal tumours: four-year follow-up results in 47 patients. Korean J Radiol. 2012;13(5):625–33.

    Article  PubMed  PubMed Central  Google Scholar 

  35. Tracy CR, Raman JD, Donnally C, Trimmer CK, Cadeddu JA. Durable oncologic outcomes after radiofrequency ablation: experience from treating 243 small renal masses over 7.5 years. Cancer. 2010;116(13):3135–42.

    Article  PubMed  Google Scholar 

  36. Balageas P, Cornelis F, Le Bras Y, et al. Ten-year experience of percutaneous image-guided radiofrequency ablation of malignant renal tumours in high-risk patients. Eur Radiol. 2013;23(7):1925–32.

    Article  CAS  PubMed  Google Scholar 

  37. Ramirez D, Ma YB, Bedir S, Antonelli JA, Cadeddu JA, Gahan JC. Laparoscopic radiofrequency ablation of small renal tumours: long-term oncologic outcomes. J Endourol. 2014;28(3):330–4.

    Article  PubMed  Google Scholar 

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Correspondence to Emily F. Kelly M.S. .

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Kelly, E.F., Leveillee, R.J. (2018). Image-Guided Radiofrequency Ablation for Small Renal Masses. In: Ahmed, K., Raison, N., Challacombe, B., Mottrie, A., Dasgupta, P. (eds) The Management of Small Renal Masses. Springer, Cham. https://doi.org/10.1007/978-3-319-65657-1_6

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  • DOI: https://doi.org/10.1007/978-3-319-65657-1_6

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