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Nails in Systemic Disease

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Scher and Daniel’s Nails

Abstract

Nails abnormalities can be readily examined by dermatologists and may be the first indication that there is an underlying systemic disease. Splinter hemorrhages are usually due to trauma, but subacute bacterial endocarditis is another possible cause. Leukonychia is more specifically associated with systemic disease, and examples include half and half nails, Terry’s nails, and Muehrke’s lines. In yellow nail syndrome, there is a classic triad of thick and yellow nails with increased transverse curvature, absent cuticles, and slow growth rate, as well as, lymphedema, and respiratory tract involvement. Nails changes are common in pregnancy, specifically increased transverse curvature, and brittleness.

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Author information

Authors and Affiliations

  1. Department of Dermatology, Weill Cornell Medicine, New York, NY, USA

    Shari R. Lipner

  2. Department of Dermatology, Sutter Medical Group, Davis, CA, USA

    Monica Lawry

  3. Alpert Medical School of Brown University, Providence, RI, USA

    George Kroumpouzos

  4. GK Dermatology, PC, South Weymouth, MA, USA

    George Kroumpouzos

  5. Weill Cornell Medicine/Dermatology, New York Hospital, New York, NY, USA

    Richard K. Scher

  6. University of Mississippi Medical Center, Dermatology & Surgery of the Skin, Jackson, MS, USA

    C. Ralph Daniel III

Authors
  1. Shari R. Lipner
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  2. Monica Lawry
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  3. George Kroumpouzos
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  4. Richard K. Scher
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  5. C. Ralph Daniel III
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Corresponding author

Correspondence to Shari R. Lipner .

Editor information

Editors and Affiliations

  1. University of Pennsylvania, Philadelphia, PA, USA

    Adam I. Rubin

  2. Brown University, Providence, RI, USA

    Nathaniel J. Jellinek

  3. Department of Dermatology, University of Mississippi Medical Center, Jackson, MS, USA

    C. Ralph Daniel III

  4. Department of Dermatology, Weill Cornell Medical College, New York, NY, USA

    Richard K. Scher

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Lipner, S.R., Lawry, M., Kroumpouzos, G., Scher, R.K., Ralph Daniel, C. (2018). Nails in Systemic Disease. In: Rubin, A.I., Jellinek, N.J., Daniel, C.R., Scher, R.K. (eds) Scher and Daniel’s Nails. Springer, Cham. https://doi.org/10.1007/978-3-319-65649-6_21

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