Abstract
This chapter discusses the epidemiology, genetics, and pathophysiology of type 1 diabetes including insulinitis and β-cell destruction in the Eisenbarth model of pathogenesis. Complications of type 1 diabetes and pregnancy are reviewed, and diagnosis and management are discussed.
References
Atkinson MA, Eisenbarth GS, Michels AW. Type 1 diabetes. Lancet. 2014;383(9911):69–82. doi:10.1016/S0140-6736(13)60591-7.
Dabelea D, Hanson RL, Bennett PH, Roumain J, Knowler WC, Pettitt DJ. Increasing prevalence of Type II diabetes in American Indian children. Diabetologia. 1998;41(8):904–10. doi:10.1007/s001250051006.
Mayer-Davis EJ, Bell RA, Dabelea D, D’Agostino R Jr, Imperatore G, Lawrence JM, Liu L, Marcovina S, Group SfDiYS. The many faces of diabetes in American youth: type 1 and type 2 diabetes in five race and ethnic populations: the SEARCH for Diabetes in Youth Study. Diabetes Care. 2009;32(Suppl 2):S99–101. doi:10.2337/dc09-S201.
Maahs DM, West NA, Lawrence JM, Mayer-Davis EJ. Epidemiology of type 1 diabetes. Endocrinol Metab Clin N Am. 2010;39(3):481–97. doi:10.1016/j.ecl.2010.05.011.
Eisenbarth GS. Type I diabetes mellitus. A chronic autoimmune disease. N Engl J Med. 1986;314(21):1360–8. doi:10.1056/NEJM198605223142106.
American Diabetes Association. Diagnosis and classification of diabetes mellitus. Diabetes Care. 2010;33(Suppl 1):S62–9. doi:10.2337/dc10-S062.
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Moore, L.E. (2018). Type 1 Diabetes. In: Moore, L. (eds) Diabetes in Pregnancy. Springer, Cham. https://doi.org/10.1007/978-3-319-65518-5_4
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DOI: https://doi.org/10.1007/978-3-319-65518-5_4
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