LTMLE with Clustering
Breastfeeding is considered best practice in early infant feeding, and is recommended by most major health organizations. However, due to the impossibility of directly allocating breastfeeding as a randomized intervention, no direct experimental evidence is available. The PROmotion of Breastfeeding Intervention Trial (PROBIT) was a cluster-randomized trial that sought to evaluate the effect of a hospital program that encouraged and supported breastfeeding, thereby producing indirect evidence of its protective effect on infant infections and hospitalizations.
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