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The Integration of Exercise and Dietary Lifestyle Interventions into Prostate Cancer Care

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Energy Balance and Prostate Cancer

Abstract

Prostate cancer (PCa) is among the most prevalent forms of cancer among American men. For many decades, androgen deprivation therapy and newer drugs inhibiting various aspects of aberrant androgen signaling, have been a mainstay of therapy and are increasingly incorporated into multimodality treatment plans for men with prostate cancer. Although improving rate of cure and promoting survival, the adverse effects of anti-androgen therapy place men at increased risk from loss of muscle mass, sarcopenic obesity, functional declines, and metabolic syndrome and its many sequela, such as cardiovascular disease. Consequently, there is growing interest in the feasibility and efficacy of implementing lifestyle interventions that have the potential to improve treatment outcomes and support quality of life and functional status men impacted by PCa patients. The purpose of the present chapter is to provide an overview of the current scientific evidence regarding the impact of dietary intervention and exercise, both separately and in combination, for men with PCa. Although the number of studies remains modest, current evidence demonstrates that exercise, diet, and combined exercise and dietary interventions can result in significant, clinically meaningful improvements in a variety of health, fitness, and quality of life outcomes among PCa patients. The emerging evidence supports the need for studies to optimize and personalize strategies integrating lifestyle exercise and dietary interventions into the multi-disciplinary treatment strategies that improve outcomes and quality of life for men with PCa.

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Correspondence to Brian C. Focht Ph.D., F.A.C.S.M., C.S.C.S. .

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Fairman, C.M., Lucas, A.R., Grainger, E., Clinton, S.K., Focht, B.C. (2018). The Integration of Exercise and Dietary Lifestyle Interventions into Prostate Cancer Care. In: Platz, E., Berger, N. (eds) Energy Balance and Prostate Cancer. Energy Balance and Cancer, vol 14. Springer, Cham. https://doi.org/10.1007/978-3-319-64940-5_8

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