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Hyperglycemia in ICU

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Metabolic Disorders and Critically Ill Patients

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Abstract

Stress hyperglycemia refers usually to a transient elevation of blood glucose level (BGL) which occurs during acute diseases in patients without previous evidence of diabetes. This metabolic disorder is frequent and can reach up to 50% of critically ill patients [1, 2]. Many data support the relationship between stress hyperglycemia and an increased morbidity and mortality. A great enthusiasm has been triggered in 2001 after the first clinical trial showing that a tight glycemic control (TGC) in intensive care unit (ICU) reduced significantly the mortality rate and improved several other outcome variables in critically ill patients [3]. However, further studies failed to confirm these results leading to question about the real benefit and external validity of a TGC in ICU [4–8]. The recent discussions and controversies revealed the complexity of the metabolic response to stress.

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Authors and Affiliations

  1. Intensive Care Unit, Hôpital Pasteur 2, 30 Voie Romaine, 06001, Nice, Cédex 1, France

    Carole Ichai

  2. IRCAN (INSERM U1081, CNRS UMR 7284), University Hospital of Nice, Nice, France

    Carole Ichai

  3. Department of Intensive Care, Erasme University Hospital, Université libre de Bruxelles, Brussels, Belgium

    Jean-Charles Preiser

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  1. Carole Ichai
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Correspondence to Carole Ichai .

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Editors and Affiliations

  1. Intensive Care Unit, Hôpital Pasteur 2, Centre Hospitalier Universitaire de Nice, Université Côte d’Azur, Nice, France

    Carole Ichai

  2. Intensive Care Unit, Hôpital Pasteur 2, Centre Hospitalier Universitaire de Nice, Université Côte d’Azur, Nice, France

    Hervé Quintard

  3. Intensive Care Unit, Hôpital Pasteur 2, Centre Hospitalier Universitaire de Nice, Université Côte d’Azur, Nice, France

    Jean-Christophe Orban

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Ichai, C., Preiser, JC. (2018). Hyperglycemia in ICU. In: Ichai, C., Quintard, H., Orban, JC. (eds) Metabolic Disorders and Critically Ill Patients. Springer, Cham. https://doi.org/10.1007/978-3-319-64010-5_17

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