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Contemporary Management of Recurrent Respiratory Papillomatosis in Children

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Recurrent Respiratory Papillomatosis

Abstract

Recurrent respiratory papillomatosis (RRP) is a rare disease, yet represents the most common benign neoplasm of the larynx in children. While the primary symptom is hoarseness, these changes in voice may go unnoticed with potentially devastating consequences due to airway obstruction. This chapter will focus on the contemporary management of RRP in children. Virology will be discussed briefly, focusing specifically on disease severity. Clinical features, including history, physical exam, and airway endoscopy with staging assessment, will be provided. The main emphasis will be directed at surgical management including cold-steel, microdebrider, and laser techniques, as well as anesthesia considerations. A brief discussion on combination therapy, in which adjuvant treatment is paired with surgical management, will be reviewed. Finally, we will present novel opportunities for personalized medicine using cell culture techniques on tumor specimens.

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Author information

Authors and Affiliations

  1. Division of Pediatric Otolaryngology, Department of Otology and Laryngology, Massachusetts Eye and Ear Infirmary, Boston, MA, 02114, USA

    Sarah N. Bowe & Christopher J. Hartnick

Authors
  1. Sarah N. Bowe
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  2. Christopher J. Hartnick
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Correspondence to Christopher J. Hartnick .

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Editors and Affiliations

  1. Department of Otolaryngology - Head and Neck Surgery, University of Toronto, Toronto, Ontario, Canada

    Paolo Campisi

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Bowe, S.N., Hartnick, C.J. (2018). Contemporary Management of Recurrent Respiratory Papillomatosis in Children. In: Campisi, P. (eds) Recurrent Respiratory Papillomatosis. Springer, Cham. https://doi.org/10.1007/978-3-319-63823-2_8

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  • DOI: https://doi.org/10.1007/978-3-319-63823-2_8

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-63822-5

  • Online ISBN: 978-3-319-63823-2

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