Impact on Quality of Life

Chapter

Abstract

Health-related quality of life has been studied in recurrent respiratory papillomatosis (RRP) using generic validated tools in both adults and children. As anticipated, the detrimental effects of this condition on quality of life are substantial and mimic those of other chronic diseases. In the absence of a validated disease-specific quality of life tool, voice-related quality of life has been used as a surrogate measure, as voice dysfunction is recognized as a predominant detrimental health effect in individuals with RRP. A plethora of voice-related quality of life tools exists to explore the physical, emotional, and social impacts of voice disorders, and several studies have confirmed the impact of RRP is consistent with other vocal diseases. Of importance, both generic and voice-specific health-related quality of life measures do not necessarily correlate well with anatomical disease severity in RRP. In addition, an impact on voice has been shown long after remission and absence of active laryngeal papilloma disease. This suggests caution should be taken in relying on anatomical disease extent as the sole outcome measure for studies of RRP interventions. Development and validation of a disease-specific quality of life measure for RRP would provide a potentially valuable tool for clinical and research outcomes but would likely require a multi-institutional collaboration.

Keywords

Recurrent respiratory papillomatosis Laryngeal papilloma Health-related quality of life Voice-related quality of life Outcome measure Voice 

Abbreviations

HRQOL

Health-related quality of life

HUI3

Health Utilities Index version 3

JORRP

Juvenile-onset recurrent respiratory papillomatosis

PVHI

Pediatric Vocal Handicap Index

PVOS

Pediatric Voice Outcome Survey

PVRQOL

Pediatric voice-related quality of life

RRP

Recurrent respiratory papillomatosis

SF36

Short Form 36

VAPP

Voice Activity and Participation Profile

VHI

Vocal Handicap Index

VHI10

Vocal Handicap Index-10

VoiSS

Voice Symptom Scale

VOS

Voice Outcome Survey

VRQOL

Voice-related quality of life

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Copyright information

© Springer International Publishing AG 2018

Authors and Affiliations

  1. 1.Division of Pediatric Otolaryngology–Head and Neck SurgeryBC Children’s HospitalVancouverCanada

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