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Monitoring Public Health Impact of HPV Vaccination on RRP

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Recurrent Respiratory Papillomatosis

Abstract

Recurrent respiratory papillomatosis (RRP) is a rare disease resulting from human papillomavirus (HPV) infection. Estimates of disease burden may vary due to non-standardized study methodology. Monitoring of RRP can characterize RRP burden, identify risk factors and susceptible populations, detect rare complications, identify opportunities for prevention, and evaluate current therapies and public health interventions. Since the 2006 introduction of HPV vaccine in the United States, monitoring may be useful for measuring vaccine impact on reducing or preventing RRP. RRP monitoring may also help identify opportunities to improve quality of life for active cases and reduce overall costs associated with disease management. Potential methods for monitoring RRP include national surveillance systems, nationally representative health surveys, registries and collaboratives, and administrative claims databases. Ideally, a national RRP registry or database may enable assessment of HPV vaccine impact on RRP burden in countries with HPV vaccination programs.

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Notes

  1. 1.

    HPV vaccination is also recommended for men who have sex with men (MSM), for transgender persons, and immunocompromised persons through age 26 years for those who were not adequately vaccinated previously.

  2. 2.

    Personal correspondence, A. Klein, Emory University

Abbreviations

4vHPV:

Quadrivalent HPV vaccine

9vHPV:

Nonavalent HPV vaccine

ACIP:

Advisory Committee on Immunization Practices

AORRP:

Adult onset recurrent respiratory papillomatosis

CDC:

Centers for Disease Control and Prevention

CMS:

Centers for Medicare and Medicaid Services

CPT:

Current Procedural Terminology

CSTE:

Council of State and Territorial Epidemiologists

DNA:

Deoxyribonucleic acid

ENT:

Ear, nose, and throat

EVMS:

Eastern Virginia Medical School

HPV:

Human papillomavirus

ICD:

International Classification of Disease

JORRP:

Juvenile onset recurrent respiratory papillomatosis

MSM:

Men who have sex with men

NCHS:

National Center for Health Statistics

NHANES:

National Health and Nutrition Examination Survey

NIH:

National Institutes of Health

NNDSS:

National Notifiable Disease Surveillance System

PPV:

Positive predictive values

RRP:

Recurrent respiratory papillomatosis

UK:

United Kingdom

US:

United States

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Acknowledgments

The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention.

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Authors and Affiliations

  1. Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, 30333, USA

    Vidisha Singh MSPH & Elissa Meites MD, MPH, FAAFP

  2. Department of Otolaryngology-HNS, Emory Voice Center, Emory University School of Medicine, Atlanta, GA, 30308, USA

    Adam Klein MD, FACS

Authors
  1. Vidisha Singh MSPH
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  2. Elissa Meites MD, MPH, FAAFP
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  3. Adam Klein MD, FACS
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Corresponding author

Correspondence to Adam Klein MD, FACS .

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Editors and Affiliations

  1. Department of Otolaryngology - Head and Neck Surgery, University of Toronto, Toronto, Ontario, Canada

    Paolo Campisi

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Singh, V., Meites, E., Klein, A. (2018). Monitoring Public Health Impact of HPV Vaccination on RRP. In: Campisi, P. (eds) Recurrent Respiratory Papillomatosis. Springer, Cham. https://doi.org/10.1007/978-3-319-63823-2_3

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  • DOI: https://doi.org/10.1007/978-3-319-63823-2_3

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