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Antimicrobial Activities of Metal Nanoparticles

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Metal Nanoparticles in Pharma

Abstract

Metals have been used since ancient times to combat infectious diseases. With the introduction of nanotechnology, metal nanoparticles have gaining increased attention as antimicrobial agents due to their broad inhibitory spectrum against bacteria, fungi, and viruses. Although silver nanoparticles have been mostly investigated due to their recognized antimicrobial properties, while other metal nanoparticles have received increasing interest as antimicrobials. These include gold, zinc oxide, titanium oxide, copper oxide, and magnesium oxide nanoparticles, since their antibacterial effects have been described. Metal nanoparticles can exert their effect on microbial cells by generating membrane damage, oxidative stress, and injury to proteins and DNA. In addition, metal nanoparticles can be associated with other nanostructures and used as carriers to antimicrobial drugs, improving the array of potential applications.

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Authors and Affiliations

  1. Laboratório de Bioquímica e Microbiologia Aplicada, Instituto de Ciência e Tecnologia de Alimentos, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil

    Adriano Brandelli, Ana Carolina Ritter & Flávio Fonseca Veras

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  1. Adriano Brandelli
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  2. Ana Carolina Ritter
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  3. Flávio Fonseca Veras
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Correspondence to Adriano Brandelli .

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  1. Nanobiotechnology laboratory, Department of Biotechnology, SGB Amravati University, Amravati, Maharashtra, India

    Mahendra Rai, Ph.D

  2. Institute of Pharmacy, Department Pharmaceutics, Biopharmaceutics & NutriCosmetics, Freie Universität Berlin, Berlin, Germany

    Ranjita Shegokar, Ph.D

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Brandelli, A., Ritter, A.C., Veras, F.F. (2017). Antimicrobial Activities of Metal Nanoparticles. In: Rai, Ph.D, M., Shegokar, Ph.D, R. (eds) Metal Nanoparticles in Pharma. Springer, Cham. https://doi.org/10.1007/978-3-319-63790-7_15

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