Summary
Knee osteoarthritis (KOA) is a mechanically induced, cytokine and enzyme-mediated disorder with different biochemical, inflammatory, and genetic signatures undergoing distinct phases and phenotypes, and encompassing all joint tissues, with pain and inflammation as the clinical and biochemical hallmarks of the disease.
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Padilla, S., Anitua, E., Fiz, N., Pompei, O., Azofra, J., Sánchez, M. (2018). The Scientific Rationale to Apply Plasma Rich in Growth Factors in Joint Tissue Pathologies: Knee Osteoarthritis. In: Anitua, E., Cugat, R., Sánchez, M. (eds) Platelet Rich Plasma in Orthopaedics and Sports Medicine. Springer, Cham. https://doi.org/10.1007/978-3-319-63730-3_7
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DOI: https://doi.org/10.1007/978-3-319-63730-3_7
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