Abstract
The nano-enabled approached for (a) nanoparticles surface chemistry needed to bind with therapeutic agent, (b) stimuli-response drug delivery and site-specific release of therapeutic agent, (c) development of pharmacological relevant personalized nanomedicine, (d) bioinformatics to manage a targeted diseases, (e) smart sensing system for diagnostics have been described in this book. However, there is a considerable explore novel biocompatible nanostructures to develop nanoformulation (NF) exhibit targeted delivery, better efficacy, and no adverse effects. Beside this novel nanostructures are also in demand to fabricate miniaturized sensing system for POC applications for rapid diagnostics needed for timey therapeutics. The state-of-the-art of advancements in personalized nanotherapeutics, related challenged, potentials future vision are discussed briefly in this chapter
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References
Fadeel B, Garcia-Bennett AE. Better safe than sorry: understanding the toxicological properties of inorganic nanoparticles manufactured for biomedical applications. Adv Drug Deliv Rev. 2010;62(3):362–74.
Thanh NTK, Green LAW. Functionalisation of nanoparticles for biomedical applications. Nano Today. 2010;5(3):213–30.
Gupta AK, Gupta M. Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications. Biomaterials. 2005;26(18):3995–4021.
Kaushik A, Jayant RD, Sagar V, Nair M. The potential of magneto-electric nanocarriers for drug delivery. Expert Opin Drug Deliv. 2014;11(10):1635–46.
Ruiz A, Nair M, Kaushik A. Recent update in NanoCure of NeuroAIDS. Sci Lett J. 2015;4:172.
Nair M, Jayant RD, Kaushik A, Sagar V. Getting into the brain: potential of nanotechnology in the management of NeuroAIDS. Adv Drug Deliv Rev. 2016;103:202–17.
Kaushik A, Jayant RD, Nair M. Advancements in nano-enabled therapeutics for neuroHIV management. Int J Nanomedicine. 2016;11:4317.
Kaushik A, Jayant RD, Nikkhah-Moshaie R, Bhardwaj V, Roy U, Huang Z, Ruiz A, Yndart A, Atluri V, El-Hage N, Khalili K. Magnetically guided central nervous system delivery and toxicity evaluation of magneto-electric nanocarriers. Scientific Rep. 2016;6:25309.
Jayant RD, Atluri VS, Agudelo M, Sagar V, Kaushik A, Nair M. Sustained-release nanoART formulation for the treatment of neuroAIDS. Int J Nanomedicine. 2015;10:1077.
Nair M, Guduru R, Liang P, Hong J, Sagar V, Khizroev S. Externally controlled on-demand release of anti-HIV drug using magneto-electric nanoparticles as carriers. Nat Commun. 2013;4:1707.
Tomitaka A, Arami H, Raymond A, Yndart A, Kaushik A, Jayant RD, Takemura Y, Cai Y, Toborek M, Nair M. Development of magneto-plasmonic nanoparticles for multimodal image-guided therapy to the brain. Nanoscale. 2017;9(2):764–73.
Kaushik A, Nikkhah-Moshaie R, Sinha R, Bhardwaj V, Atluri V, Jayant RD, Yndart A, Kateb B, Pala N, Nair M. Investigation of ac-magnetic field stimulated nanoelectroporation of magneto-electric nano-drug-carrier inside CNS cells. Scientific Rep. 2017;7:45663.
Vashist A, Kaushik A, Vashist A, Jayant RD, Tomitaka A, Ahmad S, Gupta YK, Nair M. Recent trends on hydrogel based drug delivery systems for infectious diseases. Biomater Sci. 2016;4(11):1535–53.
Kaushik A, Tiwari S, Jayant RD, Vashist A, Nikkhah-Moshaie R, El-Hage N, Nair M. Electrochemical biosensors for early stage Zika diagnostics. Trends Biotechnol. 2017;35(4):308–17.
Kaushik A, Tiwari S, Jayant RD, Marty A, Nair M. Towards detection and diagnosis of Ebola virus disease at point-of-care. Biosens Bioelectron. 2016;75:254–72.
Kaushik A, Jayant RD, Tiwari S, Vashist A, Nair M. Nano-biosensors to detect beta-amyloid for Alzheimer’s disease management. Biosens Bioelectron. 2016;80:273–87.
Kaushik A, Dixit CK. Nanobiotechnology for sensing applications: from lab to field. Oakville, Canada: Apple Academic; 2016.
Acknowledgments
Authors acknowledge NIH grants namely RO1DA027049, RO1DA034547, RO1-DA037838, RO1DA040537, and RO1DA042706.
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Kaushik, A., Kateb, B., Nair, M. (2017). Future Prospects and Vision. In: Kaushik, A., Jayant, R., Nair, M. (eds) Advances in Personalized Nanotherapeutics . Springer, Cham. https://doi.org/10.1007/978-3-319-63633-7_14
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DOI: https://doi.org/10.1007/978-3-319-63633-7_14
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