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Pre-Menopause, Menopause and Beyond pp 95–101Cite as

Oocyte Donation in Perimenopausal and Menopausal Women

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Part of the book series: ISGE Series ((ISGE))

Abstract

Reproductive menopause is recognised as a pause of reproductive ability due to the decline of ovarian reserve with age. The time period preceding menopause, called perimenopause, involves a transition period of variations in the menstrual cycle and endocrine levels. While fertility declines with age, perimenopausal conception remains a challenge regarding the chances of pregnancy achievement. Although IVF is widely used in the management of infertility in women of advanced maternal age, the extremely low pregnancy rates achieved in these patients necessitate to consider alternative options with higher success rates. Oocyte donation represents an efficacious and well-established treatment option in ART, particularly in perimenopausal and menopausal women. Higher pregnancy and delivery rates, as well as lower miscarriage rates have been reported with the use of donated oocytes in older women. However, obstetrical and neonatal complications seem to be increased in pregnancies with oocyte donation, raising ethical and social considerations. In order to minimize the risk of serious complications, appropriate management strategies with regard to oocyte donation should be evaluated after careful selection of patients. Moreover, a detailed medical evaluation and a thorough counselling of patients interested in receiving donated oocytes need to be offered.

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Authors and Affiliations

  1. Unit for Human Reproduction, First Department of OB/GYN, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece

    Basil Tarlatzis & Julia Bosdou

Authors
  1. Basil Tarlatzis
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  2. Julia Bosdou
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Correspondence to Basil Tarlatzis .

Editor information

Editors and Affiliations

  1. Professor emeritus for Gynaecological Endocrinology and Reproductive Medicine, University of Bern, Bern, Switzerland

    Martin Birkhaeuser

  2. International Society of Gynecological Endocrinology, Pisa, Italy

    Andrea R. Genazzani

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© 2018 International Society of Gynecological Endocrinology

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Tarlatzis, B., Bosdou, J. (2018). Oocyte Donation in Perimenopausal and Menopausal Women. In: Birkhaeuser, M., Genazzani, A. (eds) Pre-Menopause, Menopause and Beyond. ISGE Series. Springer, Cham. https://doi.org/10.1007/978-3-319-63540-8_7

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  • DOI: https://doi.org/10.1007/978-3-319-63540-8_7

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-63539-2

  • Online ISBN: 978-3-319-63540-8

  • eBook Packages: MedicineMedicine (R0)

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