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The Role of Chromoendoscopy and Enhanced Imaging Techniques in Inflammatory Bowel Disease Colorectal Cancer Colonoscopy Surveillance

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Diagnostic and Therapeutic Procedures in Gastroenterology

Part of the book series: Clinical Gastroenterology ((CG))

Abstract

Patients with a long-standing ulcerative colitis (UC) and extensive Crohn’s disease (CD) colitis have an approximately twofold higher risk of developing colorectal cancer. Increased duration and extent of colonic involvement contribute to the level of risk and unfortunately are not modifiable. A majority of gastrointestinal professional societies have recommended colonoscopy for the surveillance of patients with inflammatory bowel disease (IBD). Despite surveillance, IBD patients with colitis continue to be at risk for colorectal cancer secondary to missed and unrecognized dysplastic lesions at colonoscopy. Until recently, the random sampling of mucosa throughout the colon has been the primary method of surveillance. This approach to colonoscopy surveillance in IBD has been ineffective, time-consuming, and expensive and has a low diagnostic yield. According to the latest studies, most dysplastic lesions are visible to careful endoscopic inspection. This has led to a more focused approach in surveillance colonoscopy, mainly targeted biopsies of any mucosal abnormalities using chromoendoscopy (CE) and other enhanced imaging techniques including high-definition endoscopy, confocal laser endomicroscopy, endocytoscopy, and molecular imaging.

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Author information

Authors and Affiliations

  1. Division of Hospital Medicine, New York University Langone Medical Center, 550 First Avenue, New York, NY, 10016, USA

    Rotimi Ayoola

  2. Wesleyan College, 4760 Forsyth Rd, Macon, GA, 31210, USA

    Monica Mohanty

  3. Digestive Health Center, Section of Gastroenterology & Hepatology, Medical College of Georgia, Augusta University, AD 2226, 1120 15th Street, Augusta, GA, 30912, USA

    Jai Eun Lee & Humberto Sifuentes

Authors
  1. Rotimi Ayoola
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  2. Monica Mohanty
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  3. Jai Eun Lee
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  4. Humberto Sifuentes
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Corresponding author

Correspondence to Humberto Sifuentes .

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Editors and Affiliations

  1. Advanced Endoscopy, Digestive Health Center, Section of Gastroenterology & Hepatology, Medical College of Georgia, Augusta University, Augusta, Georgia, USA

    Subbaramiah Sridhar

  2. Division of Gastroenterology-Hepatology, University of Connecticut Health Center, Farmington, Connecticut, USA

    George Y. Wu

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Ayoola, R., Mohanty, M., Lee, J.E., Sifuentes, H. (2018). The Role of Chromoendoscopy and Enhanced Imaging Techniques in Inflammatory Bowel Disease Colorectal Cancer Colonoscopy Surveillance. In: Sridhar, S., Wu, G. (eds) Diagnostic and Therapeutic Procedures in Gastroenterology. Clinical Gastroenterology. Humana Press, Cham. https://doi.org/10.1007/978-3-319-62993-3_25

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  • DOI: https://doi.org/10.1007/978-3-319-62993-3_25

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  • Publisher Name: Humana Press, Cham

  • Print ISBN: 978-3-319-62991-9

  • Online ISBN: 978-3-319-62993-3

  • eBook Packages: MedicineMedicine (R0)

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