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Vitiligo pp 53-71 | Cite as

Segmental Vitiligo

  • Seung-Kyung Hann
  • Hsin-Su Yu
  • Cheng-Che Eric Lan
  • Ching-Shuang Wu
  • Yvon Gauthier
  • Laïla Benzekri
  • Alain TaïebEmail author
Chapter

Abstract

Segmental vitiligo (SV) has been historically opposed to vitiligo/nonsegmental vitiligo (NSV). However, evidence that the two forms are not mutually exclusive (delineation of mixed vitiligo) and share similar inflammatory features has challenged classical views over the last decade. SV belongs to the clinical spectrum of vitiligo, including inflammatory skin features. SV has usually an early onset and spreads rapidly in the affected segment. The hair follicle melanocytic compartment is frequently involved. Distribution in SV parallels that of other acquired pigmentation disorders such as nevus spilus, pointing out to some underlying developmental defect. Neurogenic influences have been highlighted by striking clinical observations and experimental studies. Classification of SV is needed to establish a prognosis, and two recent classifications for cephalic and truncal SV have been proposed. Segmental vitiligo is a perfect model for studying repigmentation since it is a relative stable disease with limited active melanocyte loss. Early aggressive medical treatment of SV is currently recommended.

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© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Seung-Kyung Hann
    • 1
  • Hsin-Su Yu
    • 2
  • Cheng-Che Eric Lan
    • 2
  • Ching-Shuang Wu
    • 3
  • Yvon Gauthier
    • 4
  • Laïla Benzekri
    • 5
  • Alain Taïeb
    • 4
    Email author
  1. 1.Korea Institute of Vitiligo ResearchDrs. Woo & Hann’s skin clinicSeoulSouth Korea
  2. 2.Department of DermatologyKaohsiung Medical UniversityKaohsiungTaiwan
  3. 3.Faculty of Biomedical Laboratory ScienceKaohsiung Medical UniversityKaohsiungTaiwan
  4. 4.Service de DermatologieHôpital Saint-André, CHU de BordeauxBordeauxFrance
  5. 5.Department of DermatologyCHU Ibn SinaRabatMorocco

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