Vitiligo pp 25-37 | Cite as

Vitiligo: Histopathology, Including Electron Microscopy

  • Carlo CotaEmail author
  • Daniela Kovacs


The diagnosis of vitiligo is mainly based on clinical features; thus the role of the histological evaluation is generally poorly considered. However, the increasing interest in predicting the stability of the disease has reawakened awareness of the histopathological features of vitiligo. Histopathologically, both epidermal and dermal changes characterize vitiligo, mainly in relation to the activity and duration of the disease. Microscopical alterations of vitiligo may be subtle and overlooked in routine practice; thus a clinico-pathological correlation is crucial for a proper diagnosis.


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© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Dermatopathology UnitSan Gallicano Dermatologic Institute (IRCCS)RomeItaly
  2. 2.Laboratory of Cutaneous Physiopathology and Integrated Center of Metabolomics ResearchSan Gallicano Dermatologic Institute (IRCCS)RomeItaly

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