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Vitiligo pp 141-151 | Cite as

Age and Vitiligo: Childhood, Pregnancy and Late-Onset Vitiligo

  • Steven ThngEmail author
  • Sai Yee Chuah
  • Emily Yiping Gan
Chapter

Abstract

Vitiligo usually begins in childhood or in young adults with some studies recording around half of patients with disease onset before the age of 20 years old. Childhood vitiligo tends to present more with segmental vitiligo and is associated with higher incidences of thyroid dysfunction as well as family history of autoimmune disease, significant psychological morbidity and quality of life (QOL) impairment in the patient and in the parent. Prepubertal onset of vitiligo associates with atopic dermatitis, halo naevi, family history of vitiligo and premature hair greying. When treating children with vitiligo, special considerations would include the need to coordinate treatments with school schedules and the significant psychosocial impact of the disease on children especially if they have visible lesions. Patients with vitiligo have possibly a higher incidence of worsening during pregnancy and 6 months’ post-partum. Treatment of vitiligo during pregnancy is largely influenced by how treatment may affect the foetus in utero, and treatment has to be balanced with possible adverse effects to foetus in utero. Late-onset vitiligo is an interesting subgroup of patients with vitiligo, and its prevalence ranges from 6.8% in Northern India to 14.7% in Singapore; they seem to progress faster than childhood vitiligo, and the disease progression is significantly associated with a stressful event.

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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Steven Thng
    • 1
    Email author
  • Sai Yee Chuah
    • 1
  • Emily Yiping Gan
    • 1
  1. 1.National Skin CentreSingaporeSingapore

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