Abstract
One of the most remarkable achievements in modern medicine has been the ability to replace the failing organs of one individual with those from another. Over the last 60 years, solid organ transplantation has evolved from an experimental concept to a standard of care with increasing clinical efficacy. The collaborative effort across multiple disciplines brought transplantation from the laboratory into hospitals where it has transformed the lives of thousands. Today over 100,000 individuals await a lifesaving organ transplant with an ever-widening gap between the supply of suitable organs and demand for them. While the field works to address these challenges, it is important to recognize the pioneers who have led the journey.
References
Linden, P. K. (2009). History of solid organ transplantation and organ donation. Critical Care Clinics, 25(1), 165–184.
Friedman, S. G. Credit where due. Journal of Vascular Surgery. [Internet]. (2016). Available from: http://dx.doi.org/10.1016/j.jvs.2016.04.033 .
Dangoor, J. Y., Hakim, D. N., Singh, R. P., & Hakim, N. S. (2015). Transplantation: A brief history. Experimental and Clinical Transplantation, 13(1), 1–5.
Carrel, A. Anastomose bout a bout de la jugulaire et de la carotide primitive. Lyon Med. 1902;99:114.
Carrel, A., & Guthrie, C. C. (1906). Results of a replantation of the thigh. Science, 23(584), 393–394.
Carrel, A. (1907). Heterotransplantation of blood vessels preserved in cold storage. The Journal of Experimental Medicine, 9(2), 226–228.
Morris, P. J. (2004). Transplantation — A medical miracle of the 20th century. The New England Journal of Medicine, 351(26), 2678–2680.
Starzl, T. E. (1998). Surgery: Art or science? Birth of organ transplantation. Chirurgie, 123(3), 225–228.
Gibson, T., & Medawar, P. B. (1943). The fate of skin homografts in man. Journal of Anatomy, 77(Pt 4), 299–310.4.
Medawar, P. B. (1944). The behaviour and fate of skin autografts and skin homografts in rabbits: A report to the War Wounds Committee of the Medical Research Council. Journal of Anatomy, 78(Pt 5), 176–199.
Cannon, J. A., & Longmire, W. P., Jr. (1952). Studies of successful skin homografts in the chicken; description of a method of grafting and its application as a technic of investigation. Annals of Surgery, 135(1), 60–68.
Watson, C. J. E., & Dark, J. H. (2012). Organ transplantation: Historical perspective and current practice. British Journal of Anaesthesia, 108(Suppl 1), i29–i42.
Murray, J. E., Merrill, J. P., Harrison, J. H., Wilson, R. E., & Dammin, G. J. (1963). Prolonged survival of human-kidney homografts by immunosuppressive drug therapy. The New England Journal of Medicine, 268, 1315–1323.
Starzl, T. E. (1994). The early days of transplantation. JAMA, 272(21), 1705–1705.
Goodwin, W. E., Kaufman, J. J., Mims, M. M., et al. (1963). Human renal transplantation. I. Clinical experiences with six cases of renal homotransplantation. The Journal of Urology, 89, 13–24.
Starzl, T. E., Marchioro, T. L., & Waddell, W. R. (1963). The reversal of rejection in human renal homografts with subsequent development of homograft tolerance. Surgery, Gynecology & Obstetrics, 117, 385–395.
Hill, R. B., Dahrling, B. E., Starzl, T. E., & David, R. (1967). Death after transplantation. The American Journal of Medicine, 42(3), 327–334.
Starzl, T. E., Marchioro, T. L., Hermann, G., Brittain, R. S., & Waddell, W. R. (1963). Renal homografts in patients with major donor-recipient blood group incompatibilities. Surgical Forum, 14, 214–216.
Terasaki, P. I., & McClelland, J. D. (1964). Microdroplet assay of human serum cytotoxins. Nature, 204(4962), 998–1000.
Starzl, T. E. (2015). History of liver and other splanchnic organ transplantation. In Doria, Cataldo (ed.), Contemporary liver transplantation (pp. 1–28). Springer publishers.
Starzl, T. E., Noriko, M., Amadeo, M., & Fung, J. J. (2005). History of liver and multivisceral transplantation. In Transplantation of the liver (pp. 3–22). Elsevior publishers.
Busuttil, R. W., De Carlis, L. G., Mihaylov, P. V., Gridelli, B., Fassati, L. R., & Starzl, T. E. (2012). The first report of orthotopic liver transplantation in the western world. American Journal of Transplantation, 12(6), 1385–1387.
Starzl, T. E., Porter, K. A., Francavilla, J. A., Benichou, J., & Putnam, C. W. (1977). A hundred years of the hepatotrophic controversy. Ciba Foundation Symposium, 55, 111–129.
Starlz, T. E., Kaupp, H. A., Jr., Brock, D. R., Lazarus, R. E., & Johnson, R. V. (1960). Reconstructive problems in canine liver homotransplantation with special reference to the postoperative role of hepatic venous flow. Surgery, Gynecology & Obstetrics, 111, 733–743.
Starzl, T. E., Marchioro, T. L., Vonkaulla, K. N., Hermann, G., Brittain, R. S., & Waddell, W. R. (1963). Homotransplantation of the liver in humans. Surgery, Gynecology & Obstetrics, 117, 659–676.
Zarrinpar, A., Ali, Z., & Busuttil, R. W. (2013). Liver transplantation: Past, present and future. Nature Reviews. Gastroenterology & Hepatology, 10(7), 434–440.
Starzl, T. E. (1963). Renal transplantation in identical twins. Archives of Surgery, 86(4), 600.
Starzl, T. E., Hakala, T. R., Shaw, B. W., Jr., et al. (1984). A flexible procedure for multiple cadaveric organ procurement. Surgery, Gynecology & Obstetrics, 158(3), 223–230.
Robertson, J. A. (1999). The dead donor rule. The Hastings Center Report, 29(6), 6–14.
A definition of irreversible coma. (1968). Report of the Ad Hoc Committee of the Harvard Medical School to examine the definition of brain death. JAMA, 205(6), 337–340.
Bismuth, H., & Houssin, D. (1984). Reduced-sized orthotopic liver graft in hepatic transplantation in children. Surgery, 95(3), 367–370.
Raia, S., Nery, J. R., & Mies, S. (1989). Liver transplantation from live donors. Lancet, 2(8661), 497.
Strong, R. W., Lynch, S. V., Ong, T. H., Matsunami, H., Koido, Y., & Balderson, G. A. (1990). Successful liver transplantation from a living donor to her son. The New England Journal of Medicine, 322(21), 1505–1507.
Hashikura, Y., Yasuhiko, H., Masatoshi, M., et al. (1994). Successful living-related partial liver transplantation to an adult patient. Lancet, 343(8907), 1233–1234.
Lo, C. M., Fan, S. T., Liu, C. L., et al. (1997). Adult-to-adult living donor liver transplantation using extended right lobe grafts. Annals of surgery, 226(3), 261–9; discussion 269–70.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2017 Springer International Publishing AG, part of Springer Nature
About this chapter
Cite this chapter
DuBray, B.J., Busuttil, R.W. (2017). Historical Review of Solid Organ Transplantation. In: Nadig, S., Wertheim, J. (eds) Technological Advances in Organ Transplantation. Springer, Cham. https://doi.org/10.1007/978-3-319-62142-5_1
Download citation
DOI: https://doi.org/10.1007/978-3-319-62142-5_1
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-62141-8
Online ISBN: 978-3-319-62142-5
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)