Abstract
Specific features of human-system interaction during planning of chemical syntheses are briefly discussed. In experimental part a human-controlled retro-synthesis of the hormone prostacyclin PGI2 was investigated. Some synthetic pathways to obtain PGI2 are generated and commented.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Bunin, B.A., Siesel, B., Morales, G., Bajorath, J. (eds.): Chemoinformatics: Theory, Practice & Products. Springer, Heidelberg (2007)
Gasteiger, J. (ed.): Handbook of Cheminformatics: From Data to Knowledge. Wiley, Weinheim (2003)
Grzymała-Busse, J.W., Hippe, Z.S., Mroczek, T.: Exploration of Medical Data - Artificial Intelligence in Planning Syntheses of Drugs. University of Information Technology and Management/Scientific Publisher IVG, Rzeszow-Szczecin (2015). (in Polish)
Hippe, Z.S.: Special problems of databases design and exploitation in planning of pharmaceuticals. In: 6th International Conference on Human System Interaction, Sopot, Poland, 06–08 June 2013 (2011)
Warren, S., Wyatt, P.: Organic Synthesis: The Disconnection Approach, 2nd edn. Wiley, Chichester (2008a). pp. 203–204, 253
Warren, S., Wyatt, P.: Organic Synthesis: The Disconnection Approach, 2nd edn, pp. 71–72. Wiley, Chichester (2008b)
Warren, S., Wyatt, P.: Organic Synthesis: The Disconnection Approach, 2nd edn, pp. 108–112. Wiley, Chichester (2008c)
Warren, S., Wyatt, P.: Organic Synthesis: The Disconnection Approach, 2nd edn, p. 201. Wiley, Chichester (2008d)
http://www.nobelprize.org/nobel_prizes/chemistry/laureates/1990/corey-lecture.pdf. Accessed 3 Mar 2016
https://en.wikipedia.org/wiki/Gibberellic_acid. Accessed 13 Mar 2016
http://www.organic-chemistry.org/namedreactions/saytzeff-rule.shtm. Accessed 30 Mar 2016
https://en.wikipedia.org/wiki/Wurtz_reaction. Accessed 30 Mar 2016
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2018 Springer International Publishing AG
About this chapter
Cite this chapter
Hippe, Z.S. (2018). Human Interaction in Planning Chemical Syntheses. Some Problems of Retro-Synthesis. In: Hippe, Z., Kulikowski, J., Mroczek, T. (eds) Human-Computer Systems Interaction. Advances in Intelligent Systems and Computing, vol 551. Springer, Cham. https://doi.org/10.1007/978-3-319-62120-3_6
Download citation
DOI: https://doi.org/10.1007/978-3-319-62120-3_6
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-62119-7
Online ISBN: 978-3-319-62120-3
eBook Packages: EngineeringEngineering (R0)