Skip to main content

Endocarditis

  • Chapter
  • First Online:
Cancer and Cardiovascular Disease

Abstract

Endocarditis, defined as infection of the native or prosthetic heart valve, endocardial surface or an intracardiac device, occurs worldwide and though uncommon, can be associated with considerable morbidity and mortality.

In this chapter we present some common clinical cases and discuss the treatment options.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Institutional subscriptions

References

  1. Edoute Y, Haim N, Rinkevich D, et al. Cardiac valvular vegetations in cancer patients: a prospective echocardiographic study of 200 patients. Am J Med. 1997;102:252–8.

    Article  CAS  PubMed  Google Scholar 

  2. Yusuf SW, Ali SS, Swafford J, et al. Culture-positive and culture-negative endocarditis in patients with cancer: a retrospective observational study, 1994-2004. Medicine. 2006;85:86–94.

    Article  PubMed  Google Scholar 

  3. RW T, Parkas DK, Friis S, et al. Endocarditis and risk of cancer: a Danish nationwide cohort study. Am J Med. 2013;126:58–67.

    Article  Google Scholar 

  4. Gupta A, Madani R, Mukhtar H. Streptococcus bovis endocarditis, a silent sign for colonic tumor. Colorectal Dis. 2010;12:164–71.

    Article  CAS  PubMed  Google Scholar 

  5. Cahill TJ, Prendergast BD. Infective endocarditis. Lancet. 2016;387:882–93.

    Article  PubMed  Google Scholar 

  6. Vanassche T, Peetermans WE, Herregods MC, Herijgers P, Verhamme P. Antithrombotic therapy in infective endocarditis. Expert Rev Cardiovasc Ther. 2011;9(9):1203–19.

    Article  CAS  PubMed  Google Scholar 

  7. Carapetis JR, Steer AC, Mulholland EK, Weber M. The global burden of group A streptococcal diseases. Lancet Infect Dis. 2005;5:6855.

    Article  Google Scholar 

  8. Marijon E, Ou P, Celermajer DS, et al. Prevalence of rheumatic heart disease detected by echocardiographic screening. N Engl J Med. 2007;357:470.

    Article  CAS  PubMed  Google Scholar 

  9. Gross L, Friedberg CK. Nonbacterial thrombotic endocarditis. Classification and general description. Arch Intern Med. 1936;58:620–40.

    Article  Google Scholar 

  10. Lopez JA, Ross RS, Fishbein MC, Siegel RJ. Nonbacterial thrombotic endocarditis: a review. Am Heart J. 1987;113:774–84.

    Article  Google Scholar 

  11. Whitlock RP, Sun JC, Fremes SE, Rubens FD, Teoh KH. Antithrombotic and thrombolytic therapy for valvular heart disease: antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest. 2012;141(2 Suppl):e576S–600S.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  12. Cabell CH, Jollis JG, Gail EP, Corey R, et al. Changing patient characteristics and the effect on mortality in endocarditis. Arch Intern Med. 2002;162:90–4.

    Article  PubMed  Google Scholar 

  13. Leither MD, Shroff GR, Ding S, et al. Long term survival of dialysis patients with bacterial endocarditis undergoing valvular replacement surgery in the United States. Circulation. 2013;128:344–51.

    Article  PubMed  Google Scholar 

  14. Mermel LA, Allon M, Bouza E, et al. Clinical practice guidelines for the diagnosis and management of intravascular catheter-related infection: 2009 Update by the Infectious Diseases Society of America. Clin Infect Dis. 2009;49(1):1–4.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  15. Sandoe JA, Barlow G, Chambers JB, et al. Guidelines for the diagnosis, prevention and management of implantable cardiac electronic device infection. Report of a joint Working Party project on behalf of the British Society for Antimicrobial Chemotherapy (BSAC, host organization), British Heart Rhythm Society (BHRS), British Cardiovascular Society (BCS), British Heart Valve Society (BHVS) and British Society for Echocardiography (BSE). J Antimicrob Chemother. 2015;70:325–59.

    Article  CAS  PubMed  Google Scholar 

  16. Habib G, Lancellotti P, Antunes MJ, et al. 2015 ESC Guidelines for the management of infective endocarditis: the Task Force for the Management of Infective Endocarditis of the European Society of Cardiology (ESC). Eur Heart J. 2015;36(44):3075–128.

    Article  PubMed  Google Scholar 

  17. Baddour LM, Wilson WR, Bayer AS, et al. Infective endocarditis in adults: diagnosis, antimicrobial therapy, and management of complications. A scientific statement for healthcare professionals from the American Heart Association. Circulation. 2015;132:1435–86.

    Article  CAS  PubMed  Google Scholar 

  18. Heiro M, Nikoskelainen J, Engblom E, et al. Neurologic manifestations of infective endocarditis: a 17-year experience in a teaching hospital in Finland. Arch Intern Med. 2000;160(18):2781–7. doi:10.1001/archinte.160.18.2781.

    Article  PubMed  CAS  Google Scholar 

  19. Loughrey PB, Armstrong D, Lockhart CJ. Classical eye signs in bacterial endocarditis. QJM. 2015;108(11):909–10.

    Article  CAS  PubMed  Google Scholar 

  20. Servy A, Valeyrie-Allanore L, Alla F, et al. Prognostic value of skin manifestations of infective endocarditis. JAMA Dermatol. 2014;150(5):494–500.

    Article  PubMed  Google Scholar 

  21. Cunha BA, Gill MV, Lazar JM. Acute infective endocarditis. Diagnostic and therapeutic approach. Infect Dis Clin North Am. 1996;10:811–34.

    Article  CAS  PubMed  Google Scholar 

  22. Thomas P, Allal J, Bontoux D, et al. Rheumatologic manifestations of infective endocarditis. Ann Rheum Dis. 1984;43:716–20.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  23. Yusuf SW, Sharma J, Durand JB, Banchs J. Endocarditis and myocarditis: a brief review. Expert Rev Cardiovasc Ther. 2012;10(9):1153–64.

    Article  CAS  PubMed  Google Scholar 

  24. Tattevin P, Revest M, Lefort A, Michelet C, Lortholary O. Fungal endocarditis: current challenges. Int J Antimicrob Agents. 2014;44(4):290–4. doi:10.1016/j.ijantimicag.2014.07.003. (//www.sciencedirect.com/science/article/pii/S0924857914002349). ISSN: 0924-8579.

    Article  PubMed  CAS  Google Scholar 

  25. Lefort A, Chartier L, Sendid B, Wolff M, Mainardi J-L, Podglajen I, Desnos-Ollivier M, Fontanet A, Bretagne S, Lortholary O. Diagnosis, management and outcome of Candida endocarditis. Clin Microbiol Infect. 2012;18(4):E99–109. doi:10.1111/j.1469-0691.2012.03764.x. (//www.sciencedirect.com/science/article/pii/S1198743X1461466X). ISSN: 1198-743X.

    Article  PubMed  CAS  Google Scholar 

  26. Tacke D, Koehler P, Cornely OA. Fungal endocarditis. Curr Opin Infect Dis. 2013;26:501–7.

    Article  CAS  PubMed  Google Scholar 

  27. Chan P, Ogilby JD, Segal B. Tricuspid valve endocarditis. Am Heart J. 1989;117(5):1140–6.

    Article  CAS  PubMed  Google Scholar 

  28. Heydari AA, Safari H, Sarvhad MR. Isolated tricuspid valve endocarditis. Int J Infect Dis. 2009;13:e109–11.

    Article  PubMed  Google Scholar 

  29. Forrest GN, et al. Single center experience of a vancomycin resistant enterococcal endocarditis cohort. J Infect. 2011;63:420–8.

    Article  PubMed  Google Scholar 

  30. Chomette G, Auriol M, Baubion D, de Frejacques C. Non-bacterial thrombotic endocarditis. Autopsy study, clinico-pathological correlations. Ann Med Interne (Paris). 1980;131(7):443–7.

    CAS  Google Scholar 

  31. Moyssakis I, Tektonidou MG, Vasilliou VA, Samarkos M, Votteas V, Moutsopoulos HM. Libman-Sacks endocarditis in systemic lupus erythematosus: prevalence, associations, and evolution. Am J Med. 2007;120(7):636–42.

    Article  PubMed  Google Scholar 

  32. Bathina JD, Daher IN, Plana JC, Durand J-B, Yusuf SW. Acute myocardial infarction associated with nonbacterial thrombotic endocarditis. Tex Heart Inst J. 2010;37(2):208–12.

    PubMed  PubMed Central  Google Scholar 

  33. Kim HS, Suzuki M, Lie JT, Titus JL. Nonbacterial thrombotic endocarditis (NBTE) and disseminated intravascular coagulation (DIC): autopsy study of 36 patients. Arch Pathol Lab Med. 1977;101(2):65–8.

    PubMed  CAS  Google Scholar 

  34. Delahaye JP, Poncet P, Malquarti V, Beaune J, Gare JP, Mann JM. Cerebrovascular accidents in infective endocarditis: role of anticoagulation. Eur Heart J. 1990;11(12):1074–8.

    Article  CAS  PubMed  Google Scholar 

  35. Tornos P, Almirante B, Mirabet S, Permanyer G, Pahissa A, Soler-Soler J. Infective endocarditis due to Staphylococcus aureus: deleterious effect of anticoagulant therapy. Arch Intern Med. 1999;159(5):473–5.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Syed Wamique Yusuf .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2018 Springer International Publishing AG, part of Springer Nature

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Yusuf, S.W., Napierkowki, S.C., Banchs, J., Adachi, J.A., Hassan, S.A. (2018). Endocarditis. In: Yusuf, S., Banchs, J. (eds) Cancer and Cardiovascular Disease. Springer, Cham. https://doi.org/10.1007/978-3-319-62088-6_15

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-62088-6_15

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-62086-2

  • Online ISBN: 978-3-319-62088-6

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics