Mast Cells and Interstitial Cystitis

  • Frank Aldenborg
  • Magnus FallEmail author
  • Lennart Enerbäck


Mast cells (MC) are tissue-resident immune cells that participate in first line host defense, responding to allergic challenge and pathogen attacks. Following appropriate stimulation they release immuno-modulators, and vaso- and neuroactive compounds. Early reports suggest that MCs are innervated [1] and their anatomical proximity to vasculature and nerve fibers underpin the likelihood of functioning neuro-immune interfaces. The biological role of MCs is diversified.


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Copyright information

© Springer International Publishing AG 2018

Authors and Affiliations

  • Frank Aldenborg
    • 1
  • Magnus Fall
    • 2
    Email author
  • Lennart Enerbäck
    • 1
  1. 1.Department of PathologySahlgrenska Academy at the University of GothenburgGöteborgSweden
  2. 2.Department of UrologyInstitute of Clinical Sciences, Sahlgrenska Academy at the University of GothenburgGöteborgSweden

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