Abstract
A 56-year-old person following H&N radiotherapy which included the right half of tongue. FDG PET/CT shows normal FDG uptake of the left half of tongue (hollow arrow); not to be confused with recurrent disease. The right half of tongue has atrophied following radiotherapy and is not FDG avid. Similar changes are seen following partial tongue resection.
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- 1.
Recent reports suggest HPV+ nodal disease make take longer to involute. One of the largest studies to date which specifically considered FDG PET-CT response in HPV+ oropharyngeal cancer, FDG PET-CT at 12 weeks post-chemo-radiotherapy demonstrated high NPV for loco-regional failure though with disappointing PPV and sensitivity [1].
Reference
Vainshstein JM, et al. Refining risk stratification for locoregional failure after chemoradiotherapy in human papillomavirus-associated oropharyngeal cancer. Oral Oncol. 2014;50:234.
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Wong, W.L. (2018). PET/CT in Head and Neck Tumours: Treatment Sequelae Mimicking Active Disease—A Pictorial Atlas. In: Wong, W. (eds) PET/CT in Head and Neck Cancer. Clinicians’ Guides to Radionuclide Hybrid Imaging(). Springer, Cham. https://doi.org/10.1007/978-3-319-61440-3_7
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DOI: https://doi.org/10.1007/978-3-319-61440-3_7
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