Abstract
This paper describes an ultra-low power yet robust photoplethysmographic (PPG) readout exploiting various mixed-signal processing techniques. Firstly, compressive sampling (CS) enables to reduce the LED driver power consumption by up to 30x. Feature extraction is performed in the compressed domain, using a Lomb-Scargle periodogram (LSP) to extract the average heart rate and variability, without requiring complex signal reconstruction techniques. Secondly, we demonstrate, in simulations, increased robustness through digital motion artifact reduction for PPG signals, using a spectral subtraction technique. Finally, simulations show further signal enhancement through sensor fusion, enabling electrocardiogram (ECG)-assisted PPG acquisition for cuffless blood pressure (BP) monitoring. The power consumption gains of compressive sampling and feature extraction directly from the compressed domain are demonstrated through a 172 μW compressive sampling PPG acquisition ASIC fabricated in a 0.18 μm CMOS process. The ASIC achieves up to 30x reduction in LED driver power consumption while extracting heart rate with an accuracy conforming to ANSI-AAMI standards.
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Notes
- 1.
The benefits of CS encoding and decoding, followed by feature extraction, all on the sensor node, over the conventional approach of performing feature extraction on the Nyquist rate sampled signal might not be obvious. CS-based approach can be useful in cases where high-power stimulation is involved, as in the case with PPG acquisition as well as in the cases where the maximum achievable sampling frequency of the ADC is limited [15].
- 2.
Standard database [19] PPG signals lack annotations and hence sinusoidal modulation is chosen.
- 3.
The LED driver power consumption is measured while acquiring the PPG signal of a healthy individual. At the reported power levels, the resulting photocurrent is measured to have an AC component of 45 nApp, while the DC component is measured to be 1.6 μA.
References
Wijsman, J., Grundlehner, B., Liu, H., Hermens, H., Penders, J.: Towards mental stress detection using wearable physiological sensors. In: 2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, pp. 1798–1801, Aug 2011
Allen, J.: Photoplethysmography and its application in clinical physiological measurement. Physiol. Meas. 28(3), R1 (2007)
Webster, J.G.: Design of Pulse Oximeters. Taylor & Francis Group, New York (1997)
Rhee, S., Yang, B.-H., Asada, H.: Artifact-resistant power-efficient design of finger-ring plethysmographic sensors. IEEE Trans Biomed. Eng. 48(7), 795–805 (2001)
Alhawari, M., Albelooshi, N., Perrott, M.H.: A 0.5 V < 4 μW CMOS photoplethysmographic heart-rate sensor IC based on a non-uniform quantizer. In: 2013 IEEE International Solid-State Circuits Conference Digest of Technical Papers, pp. 384–385 (2013)
Candès, E.J., Wakin, M.B.: An introduction to compressive sampling. IEEE Signal Process. Mag. 25(2), 21–30 (2008)
Pamula, V.R., Verhelst, M., Van Hoof, C., Yazicioglu, R.F.: Computationally-efficient compressive sampling for low-power pulse oximeter system. In: 2014 IEEE Biomedical Circuits and Systems Conference (BioCAS) Proceedings, pp. 69–72 (2014)
Dixon, A.M., Allstot, E.G., Gangopadhyay, D., Allstot, D.J.: Compressed sensing system considerations for ECG and EMG wireless biosensors. IEEE Trans. Biomed. Circuits Syst. 6(2), 156–166 (2012)
Ren, F., Marković, D.: A configurable 12–237 kS/s 12.8 mW sparse-approximation engine for mobile data aggregation of compressively sampled physiological signals. IEEE J. Solid-State Circuits 51(1) 68–78 (2016)
Maechler, P., Studer, C., Bellasi, D.E., Maleki, A., Burg, A., Felber, N., Kaeslin, H., Baraniuk, R.G.: VLSI design of approximate message passing for signal restoration and compressive sensing. IEEE J. Emerging Sel. Top. Circuits Syst. 2(3), 579–590 (2012)
Maechler, P., Greisen, P., Sporrer, B., Steiner, S., Felber, N., Burg, A.: Implementation of greedy algorithms for LTE sparse channel estimation. In: 2010 Conference Record of the Forty Fourth Asilomar Conference on Signals, Systems and Computers, Nov 2010
Baheti, P.K., Garudadri, H.: An ultra low power pulse oximeter sensor based on compressed sensing. In: 2009 Sixth International Workshop on Wearable and Implantable Body Sensor Networks, Jun 2009
Csavoy, A., Molnar, G., Denison, T.: Creating support circuits for the nervous system: Considerations for brain-machine interfacing. In 2009 Symposium on VLSI Circuits, Jun 2009
Pamula, V.R., Verhelst, M., Van Hoof, C., Yazicioglu, R.F.: A novel feature extraction algorithm for on the sensor node processing of compressive sampled photoplethysmography signals. In: 2015 IEEE SENSORS, pp. 1–4. IEEE (2015)
Yoo, J., Turnes, C., Nakamura, E.B., Le, C.K., Becker, S., Sovero, E.A., Wakin, M.B., Grant, M.C., Romberg, J., Emami-Neyestanak, A., Candes, E.: A compressed sensing parameter extraction platform for radar pulse signal acquisition. IEEE IEEE J. Emerging Sel. Top. Circuits Syst. 2(3), 626–638 (2012)
Rajesh, P.V., Valero-Sarmiento, J.M., Yan, L., Bozkurt, A., Van Hoof, C., Van Helleputte, N., Yazicioglu, R.F., Verhelst, M.: A 172 μW compressive sampling photoplethysmographic readout with embedded direct heart-rate and variability extraction from compressively sampled data. In: 2016 IEEE International Solid-State Circuits Conference (ISSCC), pp. 386–387. IEEE, Piscataway (2016)
Glaros, K.N., Drakakis, E.M.: A sub-mW fully-integrated pulse oximeter front-end. IEEE Trans. Biomed. Circuits Syst. 7(3), 363–375 (2013)
Pamula, V.R., Valero-Sarmiento, J.M., Yan, L., Bozkurt, A., Van Hoof, C., Van Helleputte, N., Yazicioglu, R.F., Verhelst, M.: A 172_W compressively sampled photoplethysmographic (PPG) readout ASIC with heart rate estimation directly from compressively sampled data. IEEE Trans. Biomed. Circuits Syst. 11(3), 487–496 (2017). Available online at IEEE Xplore
Goldberger, A.L., Amaral, L.A., Glass, L., Hausdorff, J.M., Ivanov, P.C., Mark, R.G., Mietus, J.E., Moody, G.B., Peng, C.-K., Stanley, H.E.: Physiobank, physiotoolkit, and physionet components of a new research resource for complex physiologic signals. Circulation 101(23), 215–220 (2000)
ANSI/AAMI-EC13: American National Standards for cardiac monitors, hearth rate meters and alarms (2002)
Tavakoli, M., Turicchia, L., Sarpeshkar, R.: An ultra-low-power pulse oximeter implemented with an energy-efficient transimpedance amplifier. IEEE Trans. Biomed. Circuits Syst. 4(1), 27–38 (2010)
Wong, A.K., Pun, K.-P., Zhang, Y.-T., Leung, K.N.: A low-power CMOS front-end for photoplethysmographic signal acquisition with robust DC photocurrent rejection. IEEE Trans. Biomed. Circuits Syst. 2(4), 280–288 (2008)
Winokur, E.S., O’Dwyer, T., Sodini, C.G.: A low-power, dual-wavelength photoplethysmogram (PPG) SoC with static and time-varying interferer removal. IEEE Trans. Biomed. Circuits Syst. 9(4), 581–589 (2015)
Boll, S.: Suppression of acoustic noise in speech using spectral subtraction. IEEE Trans. Acoust. Speech Signal Process. 27(2), 113–120 (1979)
Helleputte, N.V., Kim, S., Kim, H., Kim, J.P., Hoof, C.V., Yazicioglu, R.F.: A 160 μA biopotential acquisition IC with fully integrated IA and motion artifact suppression. IEEE Trans. Biomed. Circuits Syst. 6(6), 552–561 (2012)
Poon, C., Zhang, Y.: Cuff-less and noninvasive measurements of arterial blood pressure by pulse transit time. In: 2005 IEEE Engineering in Medicine and Biology 27th Annual Conference (2005)
Pamula, V.R., Verhelst, M., Hoof, C.V., Yazicioglu, R.F.: A 17 nA, 47.2 dB dynamic range, adaptive sampling controller for online data rate reduction in low power ECG systems. In: 2016 IEEE Biomedical Circuits and Systems Conference (BioCAS), pp. 272–275, Oct 2016
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Pamula, V.R., Van Hoof, C., Verhelst, M. (2018). An Ultra-low Power, Robust Photoplethysmographic Readout Exploiting Compressive Sampling, Artifact Reduction, and Sensor Fusion. In: Harpe, P., Makinwa, K., Baschirotto, A. (eds) Hybrid ADCs, Smart Sensors for the IoT, and Sub-1V & Advanced Node Analog Circuit Design. Springer, Cham. https://doi.org/10.1007/978-3-319-61285-0_8
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