Abstract
Increasing interest in the clinical use of probiotics in the United States is driven both by consumer enthusiasm for products marketed to have potential health benefits and by researchers inspired by the potential to prevent, treat, and mitigate disease. A limited number of studies have examined the use of probiotics as a potential tool in the antimicrobial resistance crisis. These studies include trials using probiotics to eliminate vancomycin-resistant Enterococcus colonization and to prevent multidrug-resistant organisms. These topics, along with the safety of probiotics in the healthcare setting, will be discussed in detail in this chapter. Results have been mixed, leading to ongoing controversy regarding the utility of probiotics in these settings. The conversation is limited by the quality of published studies. Specifically, there is an overall lack of uniformity in nearly all elements of study design which makes generalizability of results difficult for clinicians.
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Perry, W., Doron, S. (2018). Probiotics and Infection Prevention. In: Bearman, G., Munoz-Price, S., Morgan, D., Murthy, R. (eds) Infection Prevention. Springer, Cham. https://doi.org/10.1007/978-3-319-60980-5_22
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DOI: https://doi.org/10.1007/978-3-319-60980-5_22
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